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Highlights what we know about the pathways pursued by embryos and evolution, and stresses what we do not yet know.
This book introduces students to basic concepts in evolutionary developmental biology, for undergraduate and graduate courses.
A comparison of the genetic circuits of Homo sapiens and Drosophila reveals the evidence for deep homology.
Many of the 14,000 genes of Drosophila are involved in the development of imaginal discs. These hollow sacs of cells make adult structures during metamorphosis, and their study is crucial to comprehending how a larva becomes a fully-functioning fly. This book examines the genetic circuitry of the well-known 'fruit fly', tackling questions of cell assemblage and pattern formation, of the hows and the whys behind the development of the fly. After an initial examination of the proximity versus pedigree imperatives, the book delves into bristle pattern formation and disc development, with entire chapters devoted to the leg, wing, and eye. Extensive appendices include a glossary of protein domains, catalogues of well-studied genes, and an outline of signaling pathways. More than 30 wiring diagrams among over 60 detailed schematics clarify the text. No student or practising scientist engaged in the study of Drosophila genetics should be without this comprehensive reference.
Argues that post-crisis Wall Street continues to be controlled by large banks and explains how a small, diverse group of Wall Street men have banded together to reform the financial markets.
"Dave Hickey gets it exactly right in his preface to this collection of journalism, poetry, fiction and memoir: Lewis, who died in 1997, was indeed 'the most stone wonderful writer that nobody ever heard of.' Writing for Rolling Stone in the early '70s, he almost singlehandedly invented the movie set piece, and no one's ever improved on his flint-eyed profiles of Sam Peckinpah and the Allman Brothers. But the best piece here is his searing memoir of his white-trash Texas parents, who died in what was ruled a double suicide. Etched in acid and heart's blood, it is a terse masterpiece." —Malcolm Jones, Newsweek "The least known of the New Journalism's founding fathers, Grover Lewis has long ...
In 1963, Martin Luther King, Jr. delivered his famous ‘ I Have a Dream’ speech. Thirty years later his son registered the words ‘ I Have a Dream’ as a trademark and successfully blocked attempts to reproduce these four words. Unlike the Gettysburg Address and other famous speeches, ‘ I Have a Dream’ is now private property, even though some the speech is comprised of words written by Thomas Jefferson, a man who very much believed that the corporate land grab of knowledge was at odds with the development of civil society. Exploring the complex intersection between creativity and commerce, Hyde raises the question of how our shared store of art and knowledge might be made compatibl...
From celebrated art historian, curator, and teacher Sarah Lewis, a fascinating examination of how our most iconic creative endeavors—from innovation to the arts—are not achievements but conversions, corrections after failed attempts. The gift of failure is a riddle: it will always be both the void and the start of infinite possibility. The Rise—part investigation into a psychological mystery, part an argument about creativity and art, and part a soulful celebration of the determination and courage of the human spirit—makes the case that many of the world’s greatest achievements have come from understanding the central importance of failure. Written over the course of four years, th...