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Exploiting the Power of Group Differences
This book presents pattern-based problem-solving methods for a variety of machine learning and data analysis problems. The methods are all based on techniques that exploit the power of group differences. They make use of group differences represented using emerging patterns (aka contrast patterns), which are patterns that match significantly different numbers of instances in different data groups. A large number of applications outside of the computing discipline are also included. Emerging patterns (EPs) are useful in many ways. EPs can be used as features, as simple classifiers, as subpopulation signatures/characterizations, and as triggering conditions for alerts. EPs can be used in gene ...
Managing Information Technology Resources in Organizations in the Next Millennium
Managing Information Technology Resources in Organizations in the Next Millennium contains more than 200 unique perspectives on numerous timely issues of managing information technology in organizations around the world. This book, featuring the latest research and applied IT practices, is a valuable source in support of teaching and research agendas.
Regulatory Genomics
Research in the field of gene regulation is evolving rapidly in the ever-changing scientific environment. Advances in microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics. The study of genomic binding locations of transcription factors has enabled a more comprehensive modeling of regulatory networks. In addition, complete genomic sequences and comparison of numerous related species have demonstrated the conservation of non-coding DNA sequences, which often provide evidence for cis-regulatory binding sites. Systematic methods to decipher the regulatory mechanism are also crucial for corroborating these regulatory networks; key to these ...
Computational Methods For Understanding Bacterial And Archaeal Genomes
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses./a
Database Systems for Advanced Applications
On behalf of the Organizing Committee, we would like to welcome you to the proceedings of the 10th International Conference on Database Systems for Advanced Applications (DASFAA 2005).
Frontiers in Human Genetics
With the completion of human genome sequencing, human genetics is poised for major developments in functional genomics, molecular diagnostics, pathogenesis of complex multifactorial diseases and gene-based therapy. This book includes manuscripts from an international symposium on human genetics and gene therapy as well as articles written by a selection of young researchers in the Asia Pacific region who are actively involved in a diverse range of medical problems, including cancers, infections, hypertension and myopia. New technologies being developed in gene therapy, lab-on-chips and bioinformatics are reported. The book provides a snapshot of the diverse approaches and solutions being developed at the frontiers of human genetics.
Computational Systems Bioinformatics
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks.The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new methods, with input from computation, engineering and biology disciplines. This multidisciplinary approach to bioinformatics gives these proceedings a unique viewpoint of the field.
Data Mining and Bioinformatics
This book constitutes the thoroughly refereed post-proceedings of the First VLDB 2006 International Workshop on Data Mining and Bioinformatics, VDMB 2006, held in Seoul, Korea in September 2006 in conjunction with VLDB 2006. The 15 revised full papers cover various topics in the areas of microarray data analysis, bioinformatics system and text retrieval, application of gene expression data, and sequence analysis.
Current Topics in Computational Molecular Biology
A survey of current topics in computational molecular biology. Computational molecular biology, or bioinformatics, draws on the disciplines of biology, mathematics, statistics, physics, chemistry, computer science, and engineering. It provides the computational support for functional genomics, which links the behavior of cells, organisms, and populations to the information encoded in the genomes, as well as for structural genomics. At the heart of all large-scale and high-throughput biotechnologies, it has a growing impact on health and medicine. This survey of computational molecular biology covers traditional topics such as protein structure modeling and sequence alignment, and more recent ones such as expression data analysis and comparative genomics. It combines algorithmic, statistical, database, and AI-based methods for studying biological problems. The book also contains an introductory chapter, as well as one on general statistical modeling and computational techniques in molecular biology. Each chapter presents a self-contained review of a specific subject. Not for sale in China, including Hong Kong.
Category Theory and Computer Science
This book constitutes the refereed proceedings of the 7th International Conference on Category Theory and Computer Science, CTCS'97, held in Santa Margheria Ligure, Italy, in September 1997. Category theory attracts interest in the theoretical computer science community because of its ability to establish connections between different areas in computer science and mathematics and to provide a few generic principles for organizing mathematical theories. This book presents a selection of 15 revised full papers together with three invited contributions. The topics addressed include reasoning principles for types, rewriting, program semantics, and structuring of logical systems.
