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Cardiotoxicity of Non-Cardiovascular Drugs
Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of card...
Pediatric Radiotherapy Planning and Treatment
By becoming knowledgeable about optimal treatment methods designed specifically for childhood cancers, members of a radiotherapy team can help improve both pediatric cancer survival statistics and patients’ quality of life. Pediatric Radiotherapy Planning and Treatment is the first single, focused resource available for health care providers to accurately plan and deliver radiation therapy to children. The first section of the book discusses the statistics of pediatric cancer incidence and survival. It also reviews the literature on radiation-induced secondary malignancies, addressing the use of intensity-modulated radiation therapy (IMRT) in children. The second section presents disease-s...
Selected Health Conditions and Likelihood of Improvement with Treatment
The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to e...
Behavioral Social Work in Health Care Settings
An essential resource for social work professionals!As the focus of the health care industry shifts from predominantly hospital-based care to out-patient managed care, social workers must adapt to a new environment. Owing to changes driven by major advances in medical care knowledge, technology, and skill, new issues in ethics, practice, and policy have arisen. Behavioral Social Work in Health Care Settings addresses the impact that changing patterns in health care delivery have had (and will continue to have) on social work professionals, presenting a thoughtful collection of articles that combine research with practical experience.Behavioral Social Work in Health Care Settings looks at a r...
Advanced and Emerging Technologies in Radiation Oncology Physics
This new book educates readers about new technologies before they appear in hospitals, enabling medical physicists and clinicians to prepare for new technologies thoroughly and proactively, and provide better patient care once new equipment becomes available. Emerging technologies in imaging, treatment planning, treatment delivery, dosimetry and informatics are all discussed. The book is divided into three parts: recently developed technologies available for practice; technologies under development nearing completion; and technologies in an early stage of development that could have potential radiotherapy applications. Features: Introduces emerging technologies in imaging, treatment planning, treatment delivery, dosimetry and informatics The advantages and limitations of each technology in clinical settings are discussed, and recommendations on how to adopt the technologies are provided Critiques and improvement points are provided for researchers, in addition to suggestions on how to prepare quality assurance are provided as needed
A Guide to Outcome Modeling In Radiotherapy and Oncology
This book explores outcome modeling in cancer from a data-centric perspective to enable a better understanding of complex treatment response, to guide the design of advanced clinical trials, and to aid personalized patient care and improve their quality of life. It contains coverage of the relevant data sources available for model construction (panomics), ranging from clinical or preclinical resources to basic patient and treatment characteristics, medical imaging (radiomics), and molecular biological markers such as those involved in genomics, proteomics and metabolomics. It also includes discussions on the varying methodologies for predictive model building with analytical and data-driven ...
Pain Management and the Opioid Epidemic
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Radiobiology in Radiotherapy
The ninth annual multidisciplinary symposium on clinical oncology organized by the Royal College of Radiologists was jointly arranged with the International Society for Radiation Oncology. It was held in London in February 1987 and discussed the biological and clinical basis of the effects of radiotherapy. Wherever possible lectures by an experimental scientist were paired with those of a clinical scientist in order to emphasize clinical relevance. It is hoped that this has resulted in a widely balanced view of the subject. The volume presents an updated version of these subjects based on those talks. After surgery, radiotherapy is the main treatment used in the management of patients with c...
A Fair Trial
In A Fair Trial: The Foundations of Breast Cancer, author Dr. Steven Narod uses knowledge and expertise amassed from his career as a physician and breast cancer researcher to deliver keen insight into the many paradoxes that arise when health care professionals attempt to predict the course of breast cancer treatment. Applying decades of careful observation and study of patients, A Fair Trial goes beyond conventional thinking to explain the variation in cancer outcomes. Readers familiar with cancer treatment may be surprised by the results. A Fair Trial is a touchstone for other scientists and physicians to question the current paradigms of breast cancer screening and treatment and will lead to new ideas that will help physicians, researchers, and patients move forward towards a cure.
When Cancer Crosses Disciplines
Ever wondered if your patient''s new symptoms are a manifestation of metastatic disease, treatment effects or are altogether unrelated to the cancer diagnosis; whether herbal remedies interact with cancer treatment; when to refer for genetic testing; or how to provide informed advice regarding dietary and lifestyle modifications?. This volume answers these and many other questions, spanning from cancer prevention to palliative care. Each chapter is comprehensively referenced, to allow the reader to explore related fields in more detail. The book is unique in summarizing a large amount of information that is beyond conventional oncology textbooks. While cancer is treated by multidisciplinary ...
