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Biotechnology of Lactic Acid Bacteria
This title represents a broad review of current research on LAB and their novel applications with contributions from a number of well-known leading scientists. The book encompasses a wide range of topics including both traditional and novel developing fields, and provides unparalleled, comprehensive information on new advances of genomics, proteomics, metabolism and biodiversity of LAB. Chapters contain state-of-the-art discussions of specific LAB applications such as their use as probiotics, live vaccines and starter cultures in old and new fermented products. The safety of these microorganisms and their interactions with diverse ecosystems natural biota are also covered as well as the new applications of well-known (bacteriocins) and novel (vitamins, low-calorie sugars, etc.) metabolites produced by LAB. This book is an essential reference for established researchers and scientists, doctoral and post-doctoral students, university professors and instructors, and food technologists working on food microbiology, physiology and biotechnology of lactic acid bacteria.
Engineering Microbes for Therapy
Microbes can play protective role in human health, and the concepts of probiotics and microbiota have been well established in recent years. Probiotics have an important economic impact in food, food supplement and veterinary industry with increasing market size. Engineering microbes for therapy can lead to selection of new microbial strains and mixtures, or targeted improvement of existing microbial strains, achieved by mutagenesis, genetic engineering and synthetic biology. Engineering of microbes can also encompass the development and improvement of their dosage forms. Possible uses of engineered microbes include antigen delivery, immunomodulation, inflammation, cancer, infectious diseases and metabolic disorders. The eBook represents an up-to-date overview, shows new results, as well as demonstrates future trends in the developing field of therapeutic microbial engineering.
Next-Generation Probiotics: From Commensal Bacteria to Novel Drugs and Food Supplements
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The Human Microbiota and Chronic Disease
Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease state...
Immunomodulatory Functions of Nutritional Ingredients in Health and Disease
Nutritional immunology is a rapidly developing field. An expanding body of evidence demonstrates the impact of foods and nutritional components on gut and systemic immunity of consumers. During recent years, the implications of nutrition and nutritional intervention on prevention of disease have become accepted and has become an important tool in management of several diseases. Nutritional immunology might become even more important in the prevention of disease when the interplay between nutritional processes and immune system is better understood. Particularly, specific cellular and molecular immune responses provoked by nutrition and the role of the gut barrier and microbiota in the interplay needs more study. This content of eBook was designed to provide a timely collection on mechanistic, translational and clinical research on the interplay between foods, nutritional components and immunity in physiological and pathophysiological conditions.
Bugs as Drugs
Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for s...
Insights into Microbe-Microbe Interactions in Human Microbial Ecosystems: Strategies to be Competitive
All parts of our body having communication with the external environment such as the skin, vagina, the respiratory tract or the gastrointestinal tract are colonized by a specific microbial community. The colon is by far the most densely populated organ in the human body. The pool of microbes inhabiting our body is known as “microbiota” and their collective genomes as “microbiome”. These microbial ecosystems regulate important functions of the host, and their functionality and the balance among the diverse microbial populations is essential for the maintenance of a “healthy status”. The impressive development in recent years of next generation sequencing (NGS) methods have made po...
Health-Promoting Food Ingredients during Processing
Health-Promoting Food Ingredients during Processing presents a comprehensive science-based approach covering the latest naturally occurring bioactive compounds in seeds, dietary fiber, proteins, fermented bio-compounds, agro-industrial waste by-products, and lactic acid bacteria. A volume in the Food Biotechnology and Engineering Series, the book discusses their identification, characterization, biological activities in terms of their bioavailability, bioaccessibility, and their beneficial effects as inflammatory mediators, probiotics, antioxidants, and hypoglycemic agents, as well as in gastrointestinal digestion and colonic fermentation. Written by an international expert team of food scie...
Probiotics-modulated intestinal immunity against infectious diseases in animals
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