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This book represents the culmination of the efforts of a group of outstanding experts in vasculitis from all over the world, who have endeavored to devote their work to this book by keeping both the text and the accompanying figures and tables lucid and memorable. Here, you will find an amalgam between evidence-based medicine to one based on eminence, through an exciting combination of original contributions, structured reviews, overviews, state-of the-art articles, and even the proposal of novel pathogenetic models of disease. The book contains contributions on the etiology and pathology of vasculitis, the potential role of endothelial cells and cytokines in vascular damage and repair as well as summaries of the latest information on several primary and secondary vasculitis syndromes. It also covers selected topics such as organ-specific vasculitic involvement and quality of life issues in vasculitis. The editor and each of the authors invite you to share this journey through one of the most exciting fields of the medicine, the world of Vasculitis.
Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results in the recognition of self-antigens seen in autoimmune conditions. - Includes coverage of basic immunology, the clinical aspects of autoimmunity, and translational immunology studies in autoimmunity - Presents key concepts supported by a systematic appraisal of the most recent evidence - Assists students at all the academic levels while also being applicable to scientists who work with autoimmunity - Designed for learning, teaching, review, testing, practice and research
This book represents the culmination of the efforts of a group of outstanding experts in vasculitis from all over the world, who have endeavored to draw themselves into this volume by keeping both the text and the accompanying figures and tables lucid and memorable. The book provides practical information about the screening approach to vasculitis by laboratory analysis, histopathology and advanced image techniques, current standard treatment along with new and more specific interventions including biologic agents, reparative surgery and experimental therapies, as well as miscellaneous issues such as the extra temporal manifestations of "temporal arteritis" or the diffuse alveolar hemorrhage syndrome. The editor and each of the authors invite you to share this journey by one of the most exciting fields of the medicine, the world of Vasculitis.
Cardiovascular diseases (CVDs) are one of the leading causes of death worldwide, which brings about a major public health burden. An increasing body of literature suggests that nutritional factors strongly affect CVD risks and progression. There is consensus among researchers that nutritional deficiency, as well as nutritional excess, both increase the risk of CVDs. In addition, it is increasingly recognized that not only nutrients but also dietary patterns play a role in CVDs. Furthermore, nutritional status and diet quality is also becoming a concern in regard to CVD development and outcomes. However, CVDs are complicated diseases with various causes, which leads to inconsistencies in dete...
Featuring detailed case studies, including Dr. Blums own inspiring personal story, Healing Arthritis offers a revolutionary way to heal your gut, repair your immune system, control inflammation, and live a happier, healthier lifearthritis-free.
A guide to the natural treatment of two of the most common and damaging coinfections of Lyme disease--Bartonella and Mycoplasma • Reveals how these conditions often go undiagnosed, complicate Lyme treatment, and cause a host of symptoms--from arthritis to severe brain dysfunction • Outlines natural treatments for both infections, with herbs and supplements for specific symptoms and to combat overreactions of the immune system • Reviews the latest scientific research on Bartonella and Mycoplasma coinfections and how treatment with antibiotics is often ineffective Each year Harvard researchers estimate there are nearly 250,000 new Lyme disease infections--only 10 percent of which will be...
Durante los últimos 10 a 15 años ha habido un extraordinario desarrollo del conocimiento del proceso inflamatorio vascular, de los diversos mecanismos de amplificación y perpetuación del mismo daño, así como de los elementos que, en un intento de restituir o reparar el proceso inicial, contribuyen a la irreversibilidad del mismo. No cabe duda de que este siglo será testigo, a mediano plazo, de modificaciones importantes en el entendimiento, el conocimiento y el tratamiento de estos síndromes o padecimientos, primordialmente a través del impulso generado por el desarrollo de la biología molecular y genómica. Todos los interesados en el conocimientos de las vasculitis, perivasculitis y/o vasculopatías encontrarán en esta obra los aspectos más interesantes, completos y actualizados sobre ellos.
El libro incluye la revisión de aspectos fisiopatológicos, análisis de métodos diagnósticos desde un punto de vista didáctico y práctico, abordajes de acuerdo a los avances más importantes en la terapéutica, de acuerdo con las tendencias de manejo y prevención que la evidencia científica va marcando. Como ejemplo de ello, se revisa la utilidad de las pruebas diagnósticas en reumatología, los avances en el tratamiento de la enfermedad acidopéptica y aspectos novedosos en el manejo de la sepsis, así como las indicaciones de utilidad comprobada del doble bloqueo del eje renina-angiotensina. También incluimos aspectos relevantes sobre prevención y manejo de las complicaciones de...