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The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the fi...
Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.
Harold C. Urey (1893–1981), whose discoveries lie at the foundation of modern science, was one of the most famous American scientists of the twentieth century. Born in rural Indiana, his evolution from small-town farm boy to scientific celebrity made him a symbol and spokesman for American scientific authority. Because he rose to fame alongside the prestige of American science, the story of his life reflects broader changes in the social and intellectual landscape of twentieth-century America. In this, the first ever biography of the chemist, Matthew Shindell shines new light on Urey’s struggles and achievements in a thoughtful exploration of the science, politics, and society of the Col...