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Winner of the 2016 PEN/ESPN Award for Literary Sports Writing The true story of the game that never should have happened--and of a nation on the brink of monumental change In the fall of 1943, at the little-known North Carolina College for Negroes, Coach John McLendon was on the verge of changing basketball forever. A protégé of James Naismith, the game's inventor, McLendon taught his team to play the full-court press and run a fast break that no one could catch. His Eagles would become the highest-scoring college team in America--a basketball juggernaut that shattered its opponents by as many as sixty points per game. Yet his players faced danger whenever they traveled backcountry roads. ...
From its early days as a sport to build “muscular Christianity” among young men flooding nineteenth-century cities to its position today as a global symbol of American culture, basketball has been a force in American society. It grew through high school gymnasiums, college pep rallies, and the fits and starts of professionalization. It was a playground game, an urban game, tied to all of the caricatures that were associated with urban culture. It struggled with integration and representations of race. Today, basketball’s influence seeps into film, music, dance, and fashion. Hoops tells the story of the reciprocal relationship between the sport and the society that received it. While ma...
This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell homeostasis, and their gene mutations may cause or contribute to severe human genetic disorders, such as cystic fibrosis, neurological disease, retinal degeneration, anemia, a...
Twenty contributions examine a variety of functions reportedly mediated by cells within the natural immune system and review the diverse functional activities of the lymphoid cells. Major emphasis is on the reactivity of natural effector cells specifically within the lymphoid populations. Annotation