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Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse....
ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are linked to many intracellular signalling systems. Purinergic signalling affects a diverse range of cellular phenomena, including ion channel function, cytoskeletal dynamics, gene expression, secretion, cell proliferation, differentiation and cell death. Recently, this class of signalling molecules and receptors has been found to mediate communication between neurons and non-neuronal cells (glia) in t...
This book presents the state-of-the-art in the area of water remediation. It covers topics such as decentralized ecological wastewater treatment, applications of remote sensing and geographic information systems (GIS) in water quality monitoring and remediation, water remediation through nanotechnology, and processes used in water purification. The contents of this volume will prove useful to researchers, students, and policy makers alike.
Since 1990, Teach For America has been building a movement to end educational inequity in America. Now its founder, Wendy Kopp, shares the lessons learned from the experiences of more than 25,000 teachers and alumni who have taught and led schools in low-income communities during those years. A Chance to Make History cuts through the noise of today's debates to describe precisely what it will take to provide transformational education -- education that changes the academic and life trajectories predicted by children's socioeconomic backgrounds. Sharing her experiences in some of the country's most underserved communities, Kopp introduces leaders at the classroom, school, and system levels wh...
This book features a collection of high-quality research papers presented at the International Conference on Tourism, Technology & Systems (ICOTTS 2020), held at the University of Cartagena, in Cartagena de Indias, Colombia, from 29th to 31st October 2020. The book is divided into two volumes, and it covers the areas of technology in tourism and the tourist experience, generations and technology in tourism, digital marketing applied to tourism and travel, mobile technologies applied to sustainable tourism, information technologies in tourism, digital transformation of tourism business, e-tourism and tourism 2.0, big data and management for travel and tourism, geotagging and tourist mobility, smart destinations, robotics in tourism, and information systems and technologies.
For the vigilant writer, driven publisher or game designer, Volume 3 of the Gygaxian Fantasy World series drives forward the gathering host of information brought to you by the Gygaxian Fantasy World series. From the encampments of common folk and wanderers to the teeming streets of walled towns, this work brings the fantastic world of magic to life. Game designers captain their own creations when they master knowledge of the high and low, the hamlets and towns, cities and castles and all that accompanies life in a world of our own imagining. More than that, Everyday Life breathes strength into the arms of your imaginings with pirates and palace life, eating and entertainment, villains and vagabonds, communications and commerce. Whatever is found in the daily life of a typical fantasy world is covered herein. Sound the note of world creation with Gary Gygax's Everyday Life.
From her dorm room at Princeton University, twenty-one-year-old college senior Wendy Kopp decided to launch a movement to improve public education in America. In One Day, All Children... , she shares the remarkable story of Teach For America, a non-profit organization that sends outstanding college graduates to teach for two years in the most under-resourced urban and rural public schools in America. The astonishing success of the program has proven it possible for children in low-income areas to attain the same level of academic achievement as children in more privileged areas and more privileged schools. One Day, All Children… is not just a personal memoir. It's a blueprint for the new civil rights movement--a movement that demands educational access and opportunity for all American children.
This book features a collection of high-quality research papers presented at the International Conference on Tourism, Technology & Systems (ICOTTS 2020), held at the University of Cartagena, in Cartagena de Indias, Colombia, from 29th to 31st October 2020. The book is divided into two volumes, and it covers the areas of technology in tourism and the tourist experience, generations and technology in tourism, digital marketing applied to tourism and travel, mobile technologies applied to sustainable tourism, information technologies in tourism, digital transformation of tourism business, e-tourism and tourism 2.0, big data and management for travel and tourism, geotagging and tourist mobility, smart destinations, robotics in tourism, and information systems and technologies.