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Modeling the 3D Conformation of Genomes
This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.
Principles and Practice of Botanicals as an Integrative Therapy
The purpose of this book is to focus on major considerations in the clinical use of botanicals as an integrated therapy in current health care. The book uses an organ system approach to presenting clinical evidence on the use of botanicals for common conditions. The chapters include brief sections on background and pharmacognosy, preparation and do
Herbal Treatment of Major Depression
This unique volume presents new understandings of the neurochemical nature of major depression, and how herbs and their constituent flavonoids and terpenes appear to address some of the mechanisms now thought to be involved. It explores how recent studies of the rapid antidepressant effects of ketamine inform neuroscientists about deep intracellular mechanisms of antidepressant action that have little to do with simple enhancement of monoaminergic activity. These mechanisms include actions on PI3K, Akt, mTOR, GSK3, BDNF, and other intracellular pathways. New theories of the pathophysiology underlying major depression, such as oxidative damage, inflammation, stress and insulin resistance are then explored. Key Features: Focuses on oxidative damage, inflammation, and metabolic syndrome. Explains that a significant percentage of people treated for major depression obtain little if any relief from standard antidepressant medications. These facts lead to discussion of herbs that can be used to treat major depression, as well as consideration of the scientific basis for how these herbs act. The antidepressant properties of 66 herbs are discussed, along with dosing and safety information.
Herbal Treatment of Anxiety
Herbal Treatment of Anxiety: Clinical Studies in Western, Chinese and Ayurvedic Traditions explains the nature and types of anxiety, its neurobiology, the pathophysiology that exacerbates and perpetuates it, and the psychopharmacology of the chemical agents that relieve its manifestations. Throughout the text are discussions of Western, Chinese and Ayurvedic herbal treatments that have been clinically shown to be effective in relieving anxiety. The book also features a scientific discussion of the use of herbs and essential oils in aromatherapy and the mechanisms by which they may work. The book concludes by providing bases upon which herbs can be chosen to treat the anxiety of patients acco...
Natural Products Interactions on Genomes
Foods from natural products are a major contributor to contemporary dietary needs. The knowledge of interactions of specific natural products on genes is accumulating due to recent scientific advancements. Natural Products Interactions on Genomes focuses on recent developments in understanding human genome interactions with various natural products
Crosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?
Somatic stem cells reside in definite compartments, known as "niches", within developed organs and tissues, being able to renew themselves, differentiate and ensure tissue maintenance and repair. In contrast with the original dogmatic distinction between renewing and non-renewing tissues, somatic stem cells have been found in almost every human organism, including brain and heart. (HSCs) and mesenchymal stem cells (MSCs), that intensely interacts. HSCs represent the common precursors of all mature blood cells. (Bone, cartilage, blood vessels, adipose tissue, and.), And in the case of the skeletal muscle Supporting connective stroma). Despite this high plasticity, the claim that MSCs could be...
The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2
The 1st volume of our Research Topic "The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape” was published as an eBook in May 2016 (see: http://journal.frontiersin.org/researchtopic/2905/the-bacterial-cell-coupling-between-growth-nucleoid-replication-cell-division-and-shape). As a sign of growing interest to the topic, two workshops followed the same year: "Stochasticity in the Cell Cycle" in Jerusalem (Israel) by the Hebrew University’s Institute of Advanced Studies and EMBO's "Cell Size Regulation" in Joachimsthal (Germany). From the time of launching the first edition, several new groups have entered the field, and many established groups have made...
Nerve-Driven Immunity
“Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” summarizes, analyzes and sheds new light on an unrecognized, yet very important role of key neurotransmitters and neuropeptides in the immune system. Each chapter of the book deals with a different neurotransmitter/neuropeptide from the following list: Dopamine, Adrenaline, Noradrenaline, Acetylcholine, Glutamate, GABA, Somatostatin, Neuropeptide Y (NPY), Vasoactive intestinal polypeptide (VIP), Calcitonin gene related peptide (CGRP), Opioids and Cannabinoids. For each of these neurotransmitters/neuropeptides, the following four topics are discussed: The specific receptors for the neurotransmitter/neuropept...
Grimm Universe
800x600 An unsuspecting woman learns of her highborn heritage and finds herself entangled in a war between the Gods themselves. Red Riding Hood returns to New York in search of a serial killer who is anything but what he seems. Before she was the Goblin Queen there was only the princess Olivia. A small child whose dark lust and blood thirsty obsession against the Goblins that slaughtered her family would lead her to discover a greater power hidden within. An evil power that would consume all she was and all she could ever be until only the evil that is the Goblin Queen remained. And see for the first time the full origin of the greatest evil to inhabit the Grimm Universe...The Dark One himself! The hot new series that spotlights the Heroes and Villains of the Grimm Universe is collected here for the first time EVER!
The Art of Aromatherapy in Magick
Infuse Your Magickal Practice with the Natural Alchemy of Plants A practical guide to the magick of essential oils, this book merges scent with spell, teaching you how to incorporate potent botanical power into your unique practice. Dree Amandi Pike, a professional aromatherapist and spiritual counselor, explores what essential oils are, where to get them, and how to select the right ones for any application—mystical or mundane. With fifty-five informative essential oil profiles, this book encourages you to venture beyond lavender's familiar fragrance to create bespoke oil blends for health, spellcraft, meditation, and more. Improve your witchcraft with dozens of exercises and recipes, including Body Worship Lotion, Blessed Bubbles, Lucky Roller Perfume, and a Terracotta Protection Talisman. With this book’s safe, eco-friendly, and ethical techniques, you can skillfully harness aromatic tools to elevate your magical prowess and nurture your spiritual well-being.
