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Cognitive reserve has emerged as a powerful concept for interpreting individual differences in susceptibility to, and recovery from, brain injury or pathology. Underlying cognitive reserve is the idea that individual differences in how cognitive tasks are mediated in the brain allow some people to cope with pathology to a greater degree than others. Cognitive Reserve: Theory and Applications describes in depth the source of these individual differences. This volume provides a comprehensive review of theory, research and clinical application of the cognitive reserve. Chapters explore the theoretical underpinnings of cognitive reserve, and evidence for its existence. Various approaches for studying this concept are addressed, including epidemiologic, cognitive experimental, and neuroimaging. Possible genetic and physiologic underpinnings of cognitive reserve are presented. Application of this concept to a wide range of situations, including child development, aging, Alzheimer’s disease, stroke, HIV, and head injury is discussed. The result is an up-to-date, global treatment of cognitive reserve that will be of interest to someone new to the concept or the experienced investigator.
LONGLISTED FOR THE 2017 ORWELL PRIZE The remarkable story of a unique series of studies that have touched the lives of almost everyone in Britain today On 3rd March 1946 a survey began that is, today, the longest-running study of human development in the world, growing to encompass six generations of children, 150,000 individuals and some of the best-studied people on the planet. The simple act of observing human life has changed the way we are born, schooled, parent and die, irrevocably altering our understanding of inequality and health. This is the tale of these studies; the scientists who created and sustain them, the remarkable discoveries that have come from them. The envy of scientists around the world, they are one of Britain's best-kept secrets.
Angsty and Sinfully Sexy — Enemies to Lovers — Agent Romance! Two rogue agents play a risqué game of whodunit Tantum Maddox uses the weapon of seduction to get what he desires Nala Dekker seeks revenge for her partner’s killer There’s one name that has me reaching for the gun holstered to my leg—Tantum Maddox. The same name my partner said before he died in my arms. I searched years for the faceless man, and his name has surfaced. I jump on the first plane to Boston in chase of my revenge. But, instead of taking the ballsy bastard in for his crime, I almost end up in bed with the obscenely sexy killer! It probably would’ve been a good idea to find out what my Target looked like before I hunted him down. In this twist of betrayal and seduction, will Tantum and Nala resist killing each other? Or, when the truth unfolds, will love become the only threat to their vindictive hearts?
A Life Course Approach to Mental Disorders examines the interplay of social and biological factors in the production of a wide range of mental disorders throughout life, from the peri-natal period through to old age. The aging into adulthood of numerous birth cohorts, especially over the past twenty years, has provided increasing evidence that mental disorders previously perceived to emerge in adulthood may have their origins early in life. This book brings together, in a single resource, the research in life course epidemiology of mental disorders, forging a consensus on the current science and pointing the way forward for the field. Assembling researchers across disparate disciplines inclu...
Imagine being thirteen years old and getting into a car that’s going to drive you to a building where you’ll be locked up with nine other children. You don’t know what they’ve done, they don’t know what you’ve done. They all seem messed up and scary. All of them have secrets, but none of their secrets are as huge as the one you’re hiding from them. When will you get out? How will you get out? What is it going to be like? You don’t know. All you know is, the next time you wake up, your bedroom door will be locked. Every time you wake up. Ten children locked up, working out how to cope, how to survive, who to trust and who to avoid. One of the children has a book of spells, and...
South Asia is home to 9 of the world's 10 cities with the worst air pollution. Concentrations of fine particulate matter (PM2.5) in some of the region's most densely populated and poor areas are up to 20 times higher than what the World Health Organization considers healthy (5 micrograms per cubic meter). This pollution causes an estimated 2 million premature deaths in the region each year and results in significant economic costs. Controlling air pollution is difficult without a better understanding of the activities that cause emissions of particulate matter. Air pollution travels long distances in South Asia and gets trapped in large 'airsheds' that are shaped by climatology and geography...
Epidemiology has been defined as the study of the distribution and determinants of health states or events in defined populations and its application to the control of health problems. Psychiatric epidemiology has continued to develop and apply these core principles in relation to mental health and mental disorders. This long-awaited second edition of Practical Psychiatric Epidemiology covers all of the considerable new developments in psychiatric epidemiology that have occurred since the first edition was published. It includes new content on key topics such as life course epidemiology, gene/environment interactions, bioethics, patient and public involvement in research, mixed methods resea...
Twenty years have passed since the destruction of the Gray invasion fleet saved the worlds of the Pride; twenty years without a single sign of the Gray throughout the known universe. The lessening of tension has permitted the Guardians to focus on reclaiming the devastated planets. As the children of the Guardians come of age, a new and more deadly threat emerges. The unexplained loss of one hundred ninety-two Æthereal warriors brings them face to face with a new Gray species even as treachery and rebellion threatens the Guardian alliance, forcing them all to face the truth about their past, their present, and whether there will be a future. Genre: Science Fiction/Fantasy Read the entire bestselling AETHEREAL SERIES by Christopher W. Wilcox Sr.! AETHEREAL [The Aethereal Series Book 1] AETHEREAL REVEALED [The Aethereal Series Book 2] AETHEREAL'S CLANS [The Aethereal Series Book 3] AETHEREAL'S PRIDE [The Aethereal Series Book 4] AETHEREAL'S CHILDREN [The Aethereal Series Book 5]