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O komparativní politologii a současné české politice
Český politolog a univerzitní profesor Miroslav Novák oslavil v roce 2013 své šedesátiny, a právě proto se v této knize sešli představitelé mladší a střední generace českých politologů, aby mu vyjádřili svou úctu. Někteří z nich byli přímými žáky Miroslava Nováka, jiní nikoli, všichni se však k Novákovi hlásí, někteří jako ke svému vzoru, jiní jako k vynikajícímu a podnětnému politologovi, který svým dílem výrazně ovlivnil současnou českou politologii. Jedná se o politologii nenormativní, empirickou, komparativní, aronovskou, duvergerovskou a sartoriánskou, politologii, která si zakládá na ověřitelnosti faktů, jejich logické a nestranné analýze, na nalézání příčin a následků věcí, politologii, která vychází z ujasněných teoretických pojmů a koncepcí, která stojí na zřetelných argumentech a správnosti myšlení. V neposlední řadě je to také politologie, která usiluje o sdělnost svých závěrů, tj. o tolik potřebnou a, bohužel, zdaleka ne vždy samozřejmou srozumitelnost výkladu.
Advances in Chromatography
For six decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. The clear presentation of topics and vivid illustrations for which this series has become known make the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Describes the thermodynamics and kinetics underlying hydrophobic interaction chromatography of proteins. Outlines use of a kinetic model in the predictive modeling of evaporation processes that eliminates the need to know the composition and identity of the chemical constituents in the sample. Explores building and employing QSRR models in cyclodextrin modified high-performance liquid chromatography (HPLC). Reviews chemometric methods commonly paired with comprehensive 2D separations and key instrumental and preprocessing considerations.
Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs)
This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology.
Continuous Biopharmaceutical Processes
Provides a coherent and critical view on the potential benefits of various continuous processes in the biopharmaceutical industry.
Ion-Exchange Chromatography and Related Techniques
Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference sou...
New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Modern Approaches in Drug Discovery
Modern Approaches in Drug Discovery, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Target Identification and Validation, Cell Painting/High Content Imaging, Target ID using chemical probes, Mining the microbiome for targets, Data driven approaches for diversity and drug-likeness, Affinity-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit assessment and prioritization, Lead Optimization: fine tuning and risk mitigation, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the Intrinsically Disordered Proteins
