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The Perfect Slime
The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix int...
Biofilms and Implantable Medical Devices
Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. - Provides useful information on the fundamentals of biofilm problems in medical devices - Discusses biofilm problems in a range of medical devices - Focuses on strategies for prevention of biofilm formation
Protein Instability at Interfaces During Drug Product Development
Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.
Microscale Surface Tension and Its Applications
Building on advances in miniaturization and soft matter, surface tension effects are a major key to the development of soft/fluidic microrobotics. Benefiting from scaling laws, surface tension and capillary effects can enable sensing, actuation, adhesion, confinement, compliance, and other structural and functional properties necessary in micro- and nanosystems. Various applications are under development: microfluidic and lab-on-chip devices, soft gripping and manipulation of particles, colloidal and interfacial assemblies, fluidic/droplet mechatronics. The capillary action is ubiquitous in drops, bubbles and menisci, opening a broad spectrum of technological solutions and scientific investi...
Biofilms in Wastewater Treatment
The central theme of the book is the flow of information from experimental approaches in biofilm research to simulation and modeling of complex wastewater systems. Probably the greatest challenge in wastewater research lies in using the methods and the results obtained in one scientific discipline to design intelligent experiments in other disciplines, and eventually to improve the knowledge base the practitioner needs to run wastewater treatment plants. The purpose of Biofilms in Wastewater Treatment is to provide engineers with the knowledge needed to apply the new insights gained by researchers. The authors provide an authoritative insight into the function of biofilms on a technical and ...
Polymers as Biomaterials
Nearly 4000 years ago, the Egyptians used linen, a natural polymeric material, for suturing wounds. About 600 B.C., the Indians used other forms of natural polymers such as cotton, horse hair, and leather in repairing wounds. Wound closure procedures using silk sutures, based mostly on polypeptides, are likely to have been practiced during the second century. Surgical application of natural polymers continued to represent the major use of polymers until the twentieth century. Not too long after the development of several major synthetic polymers, their use in biomedical applications has attracted the attention of many re searchers and clinicians. Over the past few years, interest in the biom...
Microbiological Aspects of Biofilms and Drinking Water
The development of biofilms and their role in public health - particularly drinking water - is often overlooked. Ideal for anyone interested in water related issues, Microbiological Aspects of Biofilms and Drinking Water presents an overview of the public health effects associated with drinking water. It highlights the microbiological aspects relat
Dynamic Surface Phenomena
This monograph provides a comprehensive introduction into the fast developing research field of dynamic processes at liquid/gas and liquid/liquid interfaces to postgraduate students, scientists and engineers interested in the fundamentals of non-equilibrium interfacial properties. It also addresses to some extent application fields, such as foams and emulsions. Theory and experiments on dynamic adsorption layers are considered systematically and discussed with respect to processes at interfaces. It is both an introduction for beginners in the present field as well as a systematic preparation of a vast range of the current scientific investigations generalised, together with accumulated knowledge for those already being an insider. It is the first extensive review available on the subject of dynamics of adsorption and gives a general summary of the current state of adsorption kinetics theory and experiments. The book also reviews recent progress in new-designed set-ups and improved and generalised known methods for studying interfacial relaxations.
