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Sperm Acrosome Biogenesis and Function During Fertilization
Over the last decades, acrosomal exocytosis (also called the “acrosome reaction”) has been recognized as playing an essential role in fertilization. Secretion of this granule is an absolute requirement for physiological fertilization. In recent years, the study of mammalian acrosomal exocytosis has yielded some major advances that challenge the long-held, general paradigms in the field. Principally, the idea that sperm must be acrosome-intact to bind to the zona pellucida of unfertilized eggs, based largely on in vitro fertilization studies of mouse oocytes denuded of the cumulus oophorus, has been overturned by experiments using state-of-the-art imaging of cumulus-intact oocytes and fer...
Fertilization in the Spotlight: Dynamics and Mechanisms of Sperm-Egg Interaction
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Animal Models and Human Reproduction
Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo...
IVF and Assisted Reproduction
This is the first transnational history of IVF and assisted reproduction. It is a key text for scholars and students in social science, history, science and technology studies (STS), cultural studies, and gender and sexuality studies, and a resource for journalists, policymakers, and anyone interested in assisted reproduction. IVF was seen as revolutionary in 1978 when the first two IVF babies were born, in the UK and India. Assisted reproduction has now contributed to the birth of around ten million people. The book traces the work of IVF teams as they developed new techniques and laid the foundations of a multi-billion-dollar industry. It analyses the changing definitions and experience of...
Molecular and Cellular Mechanisms in Reproduction and Early Development
The Research Topic aims to support progress towards understanding the different sets of developmental processes that are absolutely required to complete all the steps essential for successful embryonic development, under physiological conditions. We sought contributions that dealt with single cells, interaction between cells as well as intra- and extracellular signal transduction. The Research Topic presents original studies covering experimental and theoretical approaches, descriptions of new methodologies, reviews and opinions.
Sperm Differentiation and Spermatozoa Function: Mechanisms, Diagnostics, and Treatment
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The Cytoskeleton and Cellular Compartmentation: Cilia as Specialized Cellular Domains
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Editors' Showcase 2022: Insights in Molecular and Cellular Reproduction
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Sperm Differentiation and Spermatozoa Function: Mechanisms, Diagnostics, and Treatment - Volume II
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Infertility and Assisted Reproduction
Infertility affects approximately 15% of couples of reproductive age. High live birth rates rely on many advanced technologies in infertility treatment, including more accurate clinical diagnosis and patient management as well as state-of-the-art in vitro fertilization (IVF) technologies. This book discusses infertility and infertility treatments such as embryo implantation, non-invasive preimplantation genetic diagnosis (PGT), oocyte cryopreservation, cryopreservation of small numbers of sperm, and embryo culture technologies. It delivers new information and data valuable to clinicians, embryologists, and others in infertility treatment.
