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While the world is grappling with the growing problem of antibiotic resistance, marine organisms offer a promising solution with their diverse repertoire of bioactive compounds. This thematic volume explores the untapped potential of marine organisms in the fight against microbial threats. The focus of the 17 featured chapters lies in highlighting the vast array of antimicrobial agents that can be found within marine environments. The chapters provide in-depth knowledge about the latest discoveries, advancements and future needs in antimicrobial research. Readers will learn about astonishing discoveries of natural compounds with remarkable antimicrobial properties and sources. The list of ag...
Modern devices, from phones and cars to houses and the appliances within them, are being designed with formidable computational power and expanded functionality. To be truly effective, these smart devices must effectively process data from their environment and experiences and make decisions based on that information. Recent Advances in Ambient Intelligence and Context-Aware Computing investigates the functionality of ubiquitous computational systems and how they may adapt to their environment to improve the quality of interaction for the end-user. This reference book will be of value to under- and post-graduate students, professionals, and researchers in networking, computer science, communications, and other information technology disciplines.
Hematology has constantly been advancing in parallel with technological developments that have expanded our understanding of the phenotypic, genetic, and molecular complexity and extreme clinical and biological heterogeneity of leukemias. This in turn allowed for developing more effective and less toxic alternative therapeutic approaches directed against critical molecular pathways in leukemic cells. The continuous and rather extensive influx of new information regarding the key features and underlying mechanisms as well as treatment options of leukemias requires frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the clinical management and experimental research of acute and chronic leukemias with comprehensive and concise information on some important theoretical and practical developments in the biology, clinical assessment, and treatment of patients with leukemias; on specific clinical scenarios such as pregnancy or age; as well as on some molecular and pathogenetic mechanisms and their respective translation into novel therapies.
How to study a media object on the web that is at the same time a documentary, a reportage, and a game which combines both fiction and non-fiction elements? Nicole Braida digs into the discursive and material structures and infrastructures of serious games, text-adventures, newsgames, interactive maps, and data visualizations, in which refugees and migrants become the subject of humanitarian discourse. Although the goal is to arouse empathy towards migrants, these »interactive practices« distinguish who is vulnerable and who is not. It supports the idea of a »migratory crisis«, which, the author argues, is actually the symptom of a deeper crisis of the humanitarian system itself.
This book represents the ninth edition of what has become an established reference work, MAJOR COMPANIES OF THE Guide to the FAR EAST & AUSTRALASIA. This volume has been carefully researched and updated since publication of the previous arrangement of the book edition, and provides more company data on the most important companies in the region. The information in the This book has been arranged in order to allow the reader to book was submitted mostly by the companies themselves, find any entry rapidly and accurately. completely free of charge. The companies listed have been selected on the grounds of Company entries are listed alphabetically within each section; the size of their sales vol...
There may be no other sailing ship in North America that has touched the lives of so many people during 80-plus years of existence as HMCS Oriole. The design of famed MIT marine architect George Owen, the pride of original owner George Gooderham, commodore of the Royal Canadian Yacht Club, the steadfast training ship of the Royal Canadian Navy for more than five decades, and ultimately "the people's boat" in her home harbours of Esquimalt and Victoria, BC, HMCS Oriole continues to add to her legacy with every new nautical adventure. Her fascinating history is captured by author and avid mariner Shirley Hewett in a narrative based on extensive interviews with Oriole's past captains and crew. Hewett listened to their stories, shared their insights and sailed the New Zealand leg of a South Pacific good-will voyage in 1998 aboard the Oriole as part of an international crew. "She is a ship that manufactures dreams," Hewett said. "Mine became to tell her many stories."
Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.
This novel text provides a concise synthesis of how the interactions between mitochondrial and nuclear genes have played a major role in shaping the ecology and evolution of eukaryotes. The foundation for this new focus on mitonuclear interactions originated from research in biochemistry and cell biology laboratories, although the broader ecological and evolutionary implications have yet to be fully explored. The imperative for mitonuclear coadaptation is proposed to be a major selective force in the evolution of sexual reproduction and two mating types in eukaryotes, in the formation of species, in the evolution of ornaments and sexual selection, in the process of adaptation, and in the evolution of senescence. The book highlights the importance of mitonuclear coadaptation to the evolution of complex life and champions mitonuclear ecology as an important subdiscipline in ecology and evolution.