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The undisputed leading text in its market, Basics of Anesthesia, 7th Edition, provides comprehensive coverage of both basic science and clinical topics in anesthesiology. Drs. Manuel C. Pardo, Jr. and Ronald D. Miller, in conjunction with many new contributors, have ensured that all chapters are thoroughly up to date and reflect the latest advances in today’s practice. Unparalleled authorship, concise text, easy-to-read chapters, and a user-friendly format make this text the #1 primer on the scope and practice of anesthesiology. Presents the combined expertise of two of the most prolific and renowned anesthesia experts worldwide, along with more than 80 expert contributing authors. Uses a ...
This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. The text reviews and discusses approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. The book intends to elaborate functional outcomes of component-to-component relationships using rodent and nonhuman primate in vitro and in vivo models that allow for the directional and quantitative description of the complete organism in response to environmental perturbations. In addition, attention has also been directed to some of the more recent methodologies, including genomics, proteomics and metabolomics, applied in the evolutionary neurobiological field.
The village of Old Mines is the oldest settlement in the state of Missouri. Lead miners were in Old Mines as early as 1719. The founding of Old Mines in 1723 coincides with the land grant awarded to Philippe Francois Renault by French authorities on June 26, 1723, to mine lead. Thus, the oldest village in Missouri began as a mining town. In 2023, the village marks three hundred years of the French in Old Mines. This book narrates the history of people in remote Louisiana and how they have kept alive a French heritage of culture and customs. The history of Old Mines is tightly bound to the Catholic faith the French settlers brought with them, the parish they founded, and the church, schools, rectories, and convents they built. The decade of the 2020s is filled with over twenty anniversaries to be marked and celebrated in the oldest mining town in Missouri, itself marking its Bicentennial in 2021. This is not a scholarly writing of history; it is a thirty-chapter narrative, grounded in research, of the continual presence of the French in Old Mines for three hundred years.