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This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Climate change is no longer merely projected to occur in the indeterminate future. It has already begun to be manifested in the weather regimes affecting agroecosystems, food production, and rural livelihoods in many regions around the world. It is a real and growing challenge to the world at large and in particular to the scientific community, which is called upon with increasing urgency to respond effectively.The second volume in the ICP Series on Climate Change Impacts, Adaptation, and Mitigation, Handbook of Climate Change and Agroecosystems: Global and Regional Aspects and Implications is published jointly by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America and Imperial College Press. The ongoing series is dedicated to elucidating the actual and potential impacts of climate change, and to formulating effective responses to this global challenge. It is designed to inform, spur, and integrate the work of leading researchers in the major regions of the world, and to further international cooperation in this crucial field.
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Strabismus Surgery is part of the acclaimed Surgical Techniques in Ophthalmology series from Jaypee Brothers Pvt Ltd. Beginning with a detailed overview of clinical strabismus, the text goes on to discuss the recent advances and techniques in strabismus surgery. More than 200 well-illustrated images and diagrams enhance this step by step approach to strabismus surgery.
Participatory governance has a long history in India and this book traces historical-intellectual trajectories of participatory governance and how older Western discourses have influenced Indian policymakers. While colonial rulers devolved power to accommodate dissenting voices, for independent India, participatory governance was a design for democratizing governance in its true sense. Participation also acted as a vehicle for localizing governance. The author draws on both Western and non-Western theoretical treatises and the book seeks to conceptualize localizing governance also as a contextual response. It also makes the argument that despite being located in different socio-economic and ...
This book delves into optics and photonic materials, describing the development of an intelligent all-optical system capable of replicating the functional building blocks of the biological brain. Starting with an analysis of biological neuronal dynamics and traversing the state of the art of neuromorphic systems developed to date, the book arrives at a description of neural networks realized through spatial soliton technology. After a brief introduction to the biology of neural networks (Chapter 1), the book delves into the description of the neuromorphic problem emphasizing the peculiarities of optical hardware developed to date. (Chapter 2). Chapter 3 is dedicated to the description of psy...
District Governor PMJF Lion VIJAY BUDHIRAJA published the Lions Directory of District 321A1 for 2016-17 as a print edition in December 2016. This Digital Edition is a replica of the printed book and enables portability of the same information and read in the Mobile Phones or eReaders. Keep Serving Be Happy is the slogan of the Governor for this year.