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The mediastinum is a hollow space within the thoracic cavity that may give rise to a wide spectrum of tumoral conditions from the benign to the intermediate to the highly malignant neoplasms. In addition, other inflammatory and infectious conditions may also arise in this space, which renders the practice of mediastinal pathology, almost a general surgical pathology practice. However, there are numerous mediastinal conditions that are important not only for diagnosis but also for treatment and clinical outcome. Due to the unusual location and because of the complexity of the tumors occurring in the mediastinum, there are only a few experts in this particular anatomic area. In fact, there are...
This text provides the necessary tools and up-to-date information on the morphological approach and most current use of ancillary techniques in the diagnosis and treatment of malignant tumors. The work is divided by sub specialty areas so that the reader can easily obtain the information desired. Features of histopathological lesions are presented in each area, as well as an up-to-date use of the different immunohistochemical stains and molecular biology features, when applicable, which are commonly used to determine treatment modalities. All sub specialty sections are written by sub specialty pathologists with experience in tumor pathology and who work in a cancer center. Each chapter is richly illustrated and properly referenced. Oncological Surgical Pathology will be of use not only for pathologists (including pathology residents and fellows), but also for oncological surgeons, oncologists and interventional radiologists.
This book offers a comprehensive overview of thoracic pathologies of surgical interest involving the lung, mediastinum, esophagus, and chest wall with the aim of providing both radiologists and thoracic surgeons with a reference of high value in everyday clinical practice. Oncologic and non-oncologic conditions are reviewed from both the radiological and the surgical point of view, each one being documented with the aid of high-quality radiologic images from several modalities (including X-ray, fluoroscopy, CT, MR, and PET), illustrations/artwork, and high-definition images from the surgical table. The postoperative anatomy and complications associated with thoracic surgery procedures are also described in detail, with provision of imaging examples that highlight aspects of importance in differentiating between normal and abnormal findings. Written by experts in the field, Diagnostic Imaging for Thoracic Surgery is exceptional in combining precise descriptions of surgical procedures with key teaching points in imaging interpretation.
User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, includi...
New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management. In this volume, an outstanding group of the world’s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of all the major types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options.
American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A
This book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Over the course of the last decade, the treatment of lung cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of lung cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of lung cancer