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Antibodies
Intended for specialists in B cell immunology, investigating such topics as movement of a monoclonal antibody from the laboratory into the clinic, the field of Fc receptors and the impact of monoclonal antibodies on diagnosis and treatment of human
Liberation Sociology
Liberation sociology is concerned with eliminating social oppressions and creating truly just societies. Liberation sociology takes sides with the oppressed and envisions an end to that oppression. Liberation social scientists featured in this book consciously try to step outside their groups or societies and view them critically. The authors examine theories and research of social scientists who ask, Social science for what purpose? and Social science for whom? Case studies offer humanistic, democratic, and activist answers. Featured researchers provide tools to increase human abilities to understand deep social realities, engage in better dialogues, and increase democratic participation in use of knowledge.Many people of all ages today continue to be attracted to sociology and other social sciences because of their promise to contribute to better political, social, and moral understandings of themselves and their social worlds-and often because they hope it will help them to build a better society. We accent the liberation potential of social science with these social science teachers and students firmly in mind.
Immunoglobulin Genes
The immunoglobulin gene complex is responsible for generating an extraordinarily wide range of antibodies, each possessing a unique antigen specificity. The Second Edition of Immunoglobulin Genes brings the reader up to date with the rapid progress in our understanding of this system. Firmly established as the definitive book on the topic, it provides a fully comprehensive account of the organization, function, rearrangement and expression of these and related genes. Since the publication of the first edition, the work has been extensively revised and updated to cover new research data on human immunoglobulin genes as well as mammalian and lower vertebrate systems. New chapters include "Soma...
Understanding Sea-level Rise and Variability
Understanding Sea-Level Rise and Variability identifies the major impacts of sea-level rise, presents up-to-date assessments of past sea-level change, thoroughly explores all of the factors contributing to sea-level rise, and explores how sea-level extreme events might change. It identifies what is known in each area and what research and observations are required to reduce the uncertainties in our understanding of sea-level rise so that more reliable future projections can be made. A synthesis of findings provides a concise summary of past, present and future sea-level rise and its impacts on society. Key Features: Book includes contributions from a range of international sea level experts Multidisciplinary Four color throughout Describes the limits of our understanding of this crucial issue as well as pointing to directions for future research The book is for everyone interested in sea-level rise and its impacts, including policy makers, research funders, scientists, students, coastal managers and engineers. Additional resources for this book can be found at: http://www.wiley.com/go/church/sealevel.
Platelets and Their Factors
Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and cli...
Antithrombotics
A number of exciting new developments have occurred during the last few years concerning the platelet-vessel wall interaction. Although they may be obvious and clear to the specialist in the field, for the clinician the area has become rather confusing. Time has come to review current knowledge on the pathophysiology of the platelet-vessel wall interaction and show how this knowledge can constitute the rationale for pharmacotherapeutic interventions. A symposium was organized in Antwerp during which a number of outstanding speakers gave an overview of what is new on a particular topic and how this information can be translated to possible clinical applications. The proceedings of the symposi...
Purinergic and Pyrimidinergic Signalling II
Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.
