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Seldin and Giebisch's The Kidney
A classic nephrology reference for over 25years, Seldin and Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the new...
Aquaporins
Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems. - Comprehensive treatment of a topical research field - Authored by world leaders in the field - Covers structural biology and physiology - Covers different experimental and biological systems - Chapters on plant and microbial systems - Extensive treatment of mammalian physiology and pathophysiology - Structural analysis excellently illustrated
Molecular Biology and Physiology of Water and Solute Transport
Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous. In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport" to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.
Breaking the Appalachian Barrier
In 1750 the Appalachian Mountains were a formidable barrier between the British colonies in the east and French territory in the west, passable only on foot or horseback. It took more than a century to break the mountain barrier and open the west to settlement. In 1751 a private Virginia company pioneered a road from Maryland to Ohio, challenging the French and Indians for the Ohio country. Several wars stalled the road, which did not start in earnest until after Ohio became a state in 1803. The stone-paved Cumberland Road--from Cumberland, Maryland, to Wheeling, Virginia--was complete by 1818 and over the next 30 years was traversed by Conestoga wagons and stagecoaches. The Baltimore and Ohio Railroad--the first general purpose railroad in the world--started in Baltimore in the 1820s and reached Wheeling by 1852, uniting east and west.
Education Statistics Quarterly
"The National Center for Education Statistics (NCES) fulfills a congressional mandate to collect and report "statistics and information showing the condition and progress of education in the United States and other nations in order to promote and accelerate the improvement of American education."
History & Crime
Revealing the cross utility potential of multiple disciplines to advance knowledge in crime studies, History & Crime showcases new research into crime from across the interdisciplinary perspectives of early modern and modern history, criminology, forensic psychology, and legal studies.
Crime in England 1880-1945
This book is an ambitious attempt to map the main changes in the criminal justice system in the Victorian period through to the twentieth century. Chapters include an examination of the growth and experience of imprisonment, policing, and probation services; the recording of crime in official statistics and in public memory; and the possibilities of research created by new electronic and on-line sources; an exploration of time, space and place, on crime, and the growth internationalisation and science-led approach of crime control methods in this period. Unusually, the book presents these issues in a way which illustrates the sources of data that informs modern crime history and discusses how criminologists and historians produce theories of crime history. Consequently, there are a series of interesting and lively debates of a thematic nature which will engage historians, criminologists, and research methods specialists, as well as the undergraduates and school students that, like the author, are fascinated by crime history.
