Seems you have not registered as a member of localhost.saystem.shop!
You may have to register before you can download all our books and magazines, click the sign up button below to create a free account.
An Introduction to Infectious Disease Modelling
Mathematical models are increasingly being used to examine questions in infectious disease control. Applications include predicting the impact of vaccination strategies against common infections and determining optimal control strategies against HIV and pandemic influenza. This book introduces individuals interested in infectious diseases to this exciting and expanding area. The mathematical level of the book is kept as simple as possible, which makes the book accessible to those who have not studied mathematics to university level. Understanding is further enhanced by models that can be accessed online, which will allow readers to explore the impact of different factors and control strategies, and further adapt and develop the models themselves. The book is based on successful courses developed by the authors at the London School of Hygiene and Tropical Medicine. It will be of interest to epidemiologists, public health researchers, policy makers, veterinary scientists, medical statisticians and infectious disease researchers.
Innovative Methods for Rare Disease Drug Development
In the United States, a rare disease is defined by the Orphan Drug Act as a disorder or condition that affects fewer than 200,000 persons. For the approval of "orphan" drug products for rare diseases, the traditional approach of power analysis for sample size calculation is not feasible because there are only limited number of subjects available for clinical trials. In this case, innovative approaches are needed for providing substantial evidence meeting the same standards for statistical assurance as drugs used to treat common conditions. Innovative Methods for Rare Disease Drug Development focuses on biostatistical applications in terms of design and analysis in pharmaceutical research and...
Handbook of Infectious Disease Data Analysis
Recent years have seen an explosion in new kinds of data on infectious diseases, including data on social contacts, whole genome sequences of pathogens, biomarkers for susceptibility to infection, serological panel data, and surveillance data. The Handbook of Infectious Disease Data Analysis provides an overview of many key statistical methods that have been developed in response to such new data streams and the associated ability to address key scientific and epidemiological questions. A unique feature of the Handbook is the wide range of topics covered. Key features Contributors include many leading researchers in the field Divided into four main sections: Basic concepts, Analysis of Outbreak Data, Analysis of Seroprevalence Data, Analysis of Surveillance Data Numerous case studies and examples throughout Provides both introductory material and key reference material
Outbreak in the Village
Outbreak in the Village is a fascinating account of the personal and professional journey of Dr. Doug Jenkinson, physician and researcher. Over the course of four decades in practice, Jenkinson traces the reemergence of whooping cough in the developed world, using his practice in the idyllic English countryside as a clinical control group. Keeping meticulous notes and indulging an itch to investigate, he explores one of history's most enigmatic and pervasive diseases. Jenkinson relates the tale of his life's work amid winsome anecdotes, relevant history, and practical advice. Told in an amiable, engaging voice with an expert balance of levity and earnestness, this story will charm casual rea...
Vaccine Protocols
Vaccine research and development is advancing at an unprecedented pace, with an increasing emphasis on rational design based upon a fundamental und- standing of the underlying molecular mechanisms. The aim of this volume is to provide a selection of contemporary protocols that will be useful to both novice and advanced practitioner alike. The variety of procedures required to design, develop, produce, and assess a vaccine is immense and covers aspects of ch- istry, biochemistry, molecular biology, cell biology, and immunology. No single volume can hope to cover these topics exclusively. Rather, here we attempt to provide a methods sourcebook focusing on hands-on practical advice. Comp- menta...
Bayesian Cost-Effectiveness Analysis of Medical Treatments
Cost-effectiveness analysis is becoming an increasingly important tool for decision making in the health systems. Cost-Effectiveness of Medical Treatments formulates the cost-effectiveness analysis as a statistical decision problem, identifies the sources of uncertainty of the problem, and gives an overview of the frequentist and Bayesian statistical approaches for decision making. Basic notions on decision theory such as space of decisions, space of nature, utility function of a decision and optimal decisions, are explained in detail using easy to read mathematics. Features Focuses on cost-effectiveness analysis as a statistical decision problem and applies the well-established optimal stat...
Racist Violence and the State
Racist Violence and the State is the first serious study to apply a comparative research-based approach to the study of racist violence in Britain, France and The Netherlands since 1945. Setting racist violence within a historical background of the post-imperialist legacy, the author presents an accessible, fascinating and highly original analysis of the development of public and state attitudes to racist violence over the past 50 years.
Medical Product Safety Evaluation
Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in t...
In a Different Key
The stunning history of autism as it has been discovered and felt by parents, children and doctors Nearly seventy-five years ago, Donald Triplett of Forest, Mississippi became the first child diagnosed with autism. In a Different Key tells the extraordinary story of the world his diagnosis created - a riveting human drama that takes us across continents and through some of the great social movements of the twentieth century. The history of autism is, above all, the story of families fighting for a place in the world for their children. It is the story of women like Ruth Sullivan, who rebelled against a medical establishment that blamed "refrigerator mothers" for causing autism, of fathers wh...
