You may have to register before you can download all our books and magazines, click the sign up button below to create a free account.
This book covers the structure and classification of adhesion molecules in relation to signaling pathways and gene expression. It discusses immunohistochemical localization, neutrophil migration, and junctional, functional, and inflammatory adhesion molecules in pathologies such as leukocyte decompression sickness and ischemia reperfusion injury. H
Dendritic Cells, Second Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry.An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on: - Imaging - Interaction of dendritic cells with viruses - Dendritic cells and dendrikines, chemokines and the endothelium - Molecules expressed in dendritic cells - Role of dendritic cells in wound healing and atherosclerosis - Delivery of apoptotic bodies - Genetic engineering of dendritic cells - Imaging - Practical aspects of clinical protocol development
In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equ...
Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV. Volume 1 of this two-volume set discusses the immunobiology of chemokines. It is divided into two parts: a) cellular targets in innate and adaptive immunity, and b) effector cell traffic-unrelated functions. Together with volume 2, which discusses the pathophysiology of chemokines, both volumes give a comprehensive overview of chemokine biology.
Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the kn...
This issue of Rheumatic Disease Clinics, guest edited by Drs. Laura Schanberg and Yukiko Kimura, will focus on Pediatric Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman. Part II, also edited by Drs. Kimura and Schanberg, will publish subsequently and cover additional topics relevant for pediatric rheumatologists. Topics discussed in this issue include but are not limited to: TMJ, CNO (CRMO), Update JIA treatment, Pharmacology of biologics in kids, Juvenile Spondylitis, Juvenile fibro update, JDM update, Pediatric Sjogrens, Localized scleroderma, Systemic Sclerosis, Uveitis, COVID-19 in pediatrics, Recent advances in pediatric vasculitis, and Autoinflammatory diseases. - Provides in-depth, clinical reviews on the latest updates in Pediatric Rheumatology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
Written by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the functional role of involved molecules and the cellular mechanisms, and addresses selected examples for their possible application in therapy -- bridging the gap between trafficking mechanisms and novel therapeutic strategies. In addition, it includes selection of proven and timesaving methods for studying cell trafficking in vitro and in vivo. The accompanying CD-ROM makes leukocyte migration videos available to a broad audience for the first time.
In recent times, both primary authors have observed that to establish a thorough and effective training program, orthopaedic trainees should undertake intensive study of orthopaedic textbooks. This should be complemented by daily practical application involving the use of questions, including both multiple-choice questions (MCQs) and short-answer questions (SAQs), along with their corresponding solutions. This recognition marked the initial phase of developing and composing a book centered around orthopaedic questions. We envisage that this publication will function as a valuable companion for each orthopaedic trainee, providing prompt access to crucial knowledge and encouraging further study. The current volume, identified as Part I, encompasses all relevant information that an orthopaedic trainee needs to adequately prepare a patient for surgery. A subsequent section, Part II, will delve into knowledge related to regional orthopaedics.
'Advances in Psychology Research' presents original research results on the leading edge of psychology. Each chapter has been carefully selected in an attempt to present substantial advances across a broad spectrum.