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Nuclear Structure and Gene Expression
Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in nuclear architecture associated with and potentially functionally related to pathologies are evaluated. Tumor cells are described from the perspective of the striking modifications in both the composition and organization of nuclear components. Nuclear Structure and Gene Expression presents concepts as well as experimental approaches, which define functionality of nuclear morphology.* Mechanisms of interaction between nuclear structure and genes* Gene expression regulation by elements of the nuclear matrix* How nuclear structure exerts a regulatory effect on other aspects of cell function/physiology
Chromatin
The Cell Nucleus: Chromatin, Part A is a collection of papers that deals with the fundamental research involving cellular responses to environmental stimuli and stress. One paper describes the ultra-structural organization of chromosomes and certain eukaryotic chromatin fractions as seen by a scanning electron microscope. The researcher investigating chromatin three-dimension ultra-structure is presented with two choices to address the technical limitations of SEM at different levels, namely, (1) electron microscope modality and (2) specimen preparation procedures. Another paper explains the extensive postmortem changes in properties occurring in nuclear preparations during purification and ...
Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010
The13thInternationalConferenceonMedicalImageComputingandComputer- Assisted Intervention, MICCAI 2010, was held in Beijing, China from 20-24 September,2010.ThevenuewastheChinaNationalConventionCenter(CNCC), China’slargestandnewestconferencecenterwith excellentfacilities andaprime location in the heart of the Olympic Green, adjacent to characteristic constr- tions like the Bird’s Nest (National Stadium) and the Water Cube (National Aquatics Center). MICCAI is the foremost international scienti?c event in the ?eld of medical image computing and computer-assisted interventions. The annual conference has a high scienti?c standard by virtue of the threshold for acceptance, and accordingly MICC...
Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006
The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This first volume includes 114 contributions related to bone shape analysis, robotics and tracking, segmentation, analysis of diffusion tensor MRI, and much more.
Advances in Enzyme Regulation
Volume 42 lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies. This volume contains papers of 25 outstanding scientists working at the cutting edge of metabolic regulation. Much of the volume focuses on novel aspects of signal transduction with an emphasis on nuclear expression. One of the highlights of this volume is the Special Symposium Lecture. This was given for 15 years by Sir Hans A. Krebs who passed away 20 years ago. It was now given by Professor Sir Hans L. Kornberg, University Professor at Boston University. These volumes continue to be a source of information and inspiration and a laboratory and advanced teaching companion. The immediate and long-range significance of these cutting-edge presentations of these novel topics should be immediately clear to the reader.
Prostate Cancer
This book embraces the wide field of prostate cancer genetics, biology, and therapy. It seems most appropriate to dedicate it to Donald S. Coffey, PhD, whose research vision is an inspiration to his colleagues and friends. Unraveling the secrets of prostate cancer is an intricate and sometimes frustrating process involving many researchers and many institutions. No one has seen through to the end of this road, and the list of researchers who have contributed to our understanding of the disease processes of prostate cancer is already a long one. But Donald Coffey stands out in his personal qualities as surely as in his roles as teacher and researcher. In the dedicatory article that begins thi...
MICCAI 2005
The two-volume set LNCS 3749 and LNCS 3750 constitutes the refereed proceedings of the 8th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2005, held in Palm Springs, CA, USA, in October 2005. Based on rigorous peer reviews the program committee selected 237 carefully revised full papers from 632 submissions for presentation in two volumes. The first volume includes all the contributions related to image analysis and validation, vascular image segmentation, image registration, diffusion tensor image analysis, image segmentation and analysis, clinical applications - validation, imaging systems - visualization, computer assisted diagnosis, cellular and molecular image analysis, physically-based modeling, robotics and intervention, medical image computing for clinical applications, and biological imaging - simulation and modeling. The second volume collects the papers related to robotics, image-guided surgery and interventions, image registration, medical image computing , structural and functional brain analysis, model-based image analysis, image-guided intervention: simulation, modeling and display, and image segmentation and analysis.
Essential Biochemistry
Essential Biochemistry, 5th Edition is comprised of biology, pre-med and allied health topics and presents a broad, but not overwhelming, base of biochemical coverage that focuses on the chemistry behind the biology. This revised edition relates the chemical concepts that scaffold the biology of biochemistry, providing practical knowledge as well as many problem-solving opportunities to hone skills. Key Concepts and Concept Review features help students to identify and review important takeaways in each section.
