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Infectious diseases are still leading cause of mortality around the world. Of particular importance in this regard are the intracellular pathogens, which dwell inside the host and manipulate host’s machinery for their growth. These include pathogens like Brucella abortus, Listeria monocytogenes, Chlamydia trachomatis, Coxiella burnetii, Mycobacterium tuberculosis, Salmonella enterica, etc. These pathogens have evolved multiple mechanisms to survive in intracellular niche. The host in turn tries to reprogram its activities to combat their growth. This host-pathogen co-evolution warrants detailed study to probe the ever-changing virulence repertoire of the pathogen, that can be used for pathogen targeting. Through this topic, we would like to explore the lesser explored area of host pathogen interactions. Studying host-pathogen crosstalk at their interface will help us in understanding this complex biology and might prove beneficial in development of new therapeutic targets. Understanding the holistics of host-pathogen interaction, will pave way for development of host-directed therapies.
Leprosy is one of the oldest recorded debilitating diseases affecting mankind, the immunopathology of which is characterized by fluctuating granulomatous inflammation that targets mainly skin and peripheral nerve. The disease is caused by infection with Mycobacterium leprae, a slow growing obligatory intracellular and non-cultivatable organism. The disease is manifested with diverse pathology due to varied immune (both innate and adaptive) responses of the hosts as a result of cognate interaction with the organism. Of note, leprosy can be regarded as a unique model to elucidate the complexity of host immunity at both skin and systemic levels.
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Buku ini memberikan pemahaman yang jelas terkait dengan Solusi Menurunkan Stigma & Stress Psikologi penanganan penyakit Kusta tersebut, Kusta adalah penyakit menular yang disebabkan oleh Mycobacterium leprae yang mengenai kulit dan saraf perifer yang menyebabkan infeksi dan akhirnya menimbulkan luka, dan kebutaan. Social capital dipahami sebagai sumber daya tertanam dalam jaringan sosial individu dengan harapan adanya pengembalian sumber daya yang lebih baik, memperkirakan sejauh mana potensi sumber daya mampu menghasilkan keuntungan bagi Individu dalam jaringan. Social capital terbukti berpengaruh terhadap stress psikologi penderita kusta, semakin baik social capital dapat menurunkan stress psikologis. Buku ini berisikan beberapa Bab - Bab yang akan membahas tentang pentingnya penanganan Solusi Praktis Menurunkan Stigma & Stress Psikologis Pengobatan Kusta
An LGBTQ YA "sci-fi romp" (Kirkus), The Last 8 is a thrilling high-stakes survival story about the last eight teenagers left on Earth after aliens attack, praised as "An extravaganza of nonstop action" (School Library Journal) Extinction was just the beginning... Clover Martinez has always been a survivor, which is the reason she isn't among the dead when aliens invade and destroy Earth as she knows it. Clover is convinced she's the only one left until she hears a voice on the radio urging her to go to the former Area 51. When she arrives, she's greeted by a band of misfits who call themselves The Last Teenagers on Earth. Only they aren't the ragtag group of heroes Clover was expecting. The ...
Poverty and Shared Prosperity 2016 is the first of an annual flagship report that provides a global audience comprising development practitioners, policy makers, researchers, advocates, and citizens in general with the latest and most accurate estimates on trends in global poverty and shared prosperity. This edition documents trends in inequality and identifies recent country experiences that have been successful in reducing inequalities, provides key lessons from those experiences, and synthesizes the rigorous evidence on public policies that can shift inequality in a way that bolsters poverty reduction and shared prosperity in a sustainable manner.Specifically, the report addresses the fol...