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The two-volume publication reflects on the Rubin Foundation's art and social justice initiatives over the last six years, including thematic essays, roundtable discussions, and newly commissioned artworks. An Incomplete Archive of Artistic Activism is a publication in two volumes, documenting the Rubin Foundation's art and social justice mission, serving as a critical and educational resource for those interested in activist art practices and philanthropy. One volume highlights the emergence of a cultural shift, addressing art's role in the formation of both community and justice, featuring essays by Andre Lepecki and Lucy Lippard, thematic roundtables with cultural producers, and newly comm...
Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug discovery on a wide variety of areas of medicinal chemistry. It will prove to be an invaluable resource for medicinal chemists working in academia and industry, as well as anyone interested in novel drug discovery techniques.
Jillian Tamaki, co-author of This One Summer, picks the best graphic pieces of the year. "The pieces I chose were those that stuck with me, represented something important about comics in this moment, and exemplified excellence of the craft. Surveying the final collection, I'm moved by the variety of individual approaches. There are so many ways to make us care about little marks on a page."--Jillian Tamaki, from the introduction The Best American Comics 2019 showcases the work of established and up-and-coming artists, collecting work found in the pages of graphic novels, comic books, periodicals, zines, online, in galleries, and more, highlighting the kaleidoscopic diversity of the comics form today. Featuring Vera Brosgol, Eleanor Davis, Nick Drnaso, Margot Ferrick, Ben Passmore, John Porcellino, Joe Sacco, Lauren Weinstein, Lale Westvind, and others.
This book provides assistance in preparing for and conducting screening or diagnostic ultrasound examinations of the fetal brain in all stages of pregnancy. Readers are provided with: abundantly illustrated descriptions of studies conducted on normal brain structures using all conventional and 3D/4D ultrasound techniques; a detailed description of the main structures of the brain; photographs of fetal pathology specimens that may be used to compare the results of imaging techniques with the anatomical reality; and practical advice and technical tips. The second part of this book presents a clear and informative overview of fetal brain pathologies, combining a wealth of detailed images and precise descriptions.
The thrilling first adventure in the classic D&D fantasy series, the Dark Elf Trilogy—perfect for fans of the tabletop RPG and Dungeons & Dragons: Honor Among Thieves. Discover the origin story of one of the greatest heroes of the Forgotten Realms: drow ranger Drizzt Do’Urden. As the third son of Mother Malice and weaponmaster Zaknafein, Drizzt Do’Urden must be sacrificed to Lolth, the evil Spider Queen, per the traditions of their matriarchal drow society. But with the unexpected death of his older brother, young Drizzt is spared—though still at the mercy of his abusive sisters. As Drizzt grows older, and proves himself to be a formidable warrior at Melee-Magthere Academy, he realiz...
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.