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Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtu...
This Methods in Molecular Biology book offers methods for studying inflammasome function, including generation of inflammasome stimuli, monitoring of caspase-1 activity and processing, activation of IL-1β cytokines, plus lab protocols, material lists and tips.
Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divid...
In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.
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A captivating portrait of some of Charles DickensOCO most memorable female characters presented by popular actress Miriam Margolyes to accompany her hugely successful one-woman show touring the world in 2012. In his novels Dickens presents a series of unrivalled portraits of women, young and old. From Little Nell to Miss Havisham, these girls and women speak to us today, making us laugh and sometimes cry. The popular British actress Miriam Margolyes will be touring the world in 2012, the bicentenary of Dickens birth, with a one-woman show about DickensOCO women, and this book accompanies the show by building on the script and expanding to include many more of the female characters Dickens described and analysed so astutely in his novels. ?Mrs Pipchin was a marvellous ill-favoured, ill-conditioned old lady, of a stooping figure, with a mottled face, like bad marble, a hook nose, and a hard grey eye, that looked as if it might have been hammered at on an anvil without sustaining any injury.OCO"