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Imaging Neuroinflammation
Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more. - Explains how inflammation in the central nervous system impacts tissue microstructure - Presents imaging methods that are useful for assessing neuroinflammation - Describes preclinical models of neuroinflammation - Reviews the role of neuroinflammation in human injury and disease states
Quantitative Perfusion MRI
Quantitative Perfusion MRI: Techniques, Applications, and Practical Considerations, Volume 11 clearly and carefully explains the basic theory and MRI techniques for quantifying perfusion non-invasively in deep tissue, covering all aspects of perfusion imaging, from acquisition requirements to selection of contrast agents and appropriate pharmacokinetic models and for reliable quantification in different diseases and tissue types. Specifically, this book enables the reader to understand what microvascular functional parameters can be measured with perfusion MRI, learn the basic techniques to measure perfusion in different organs, apply the appropriate perfusion MRI technique to the organ of i...
The Chemistry of Hyperpolarized Magnetic Resonance Probes
The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included. - Helps readers understand the structural features that determine the properties of HP-probes, such as chemical shift and relaxation times - Aids readers in selecting stable isotope labeled probes for hyperpolarized NMR/MRI applications - Teachers readers how to use the most appropriate synthetic methodology for the labeled probes - Covers how to find the most suitable polarization technique (DNP, PHIP etc.) for the probe
Ultra-High Field Neuro MRI
Ultra-High Field Neuro MRI is a comprehensive reference and educational resource on the current state of neuroimaging at ultra-high field (UHF), with an emphasis on 7T. Sections cover the MR physics aspects of UHF, including the technical challenges and practical solutions that have enabled the rapid growth of 7T MRI. Individual chapters are dedicated to the different techniques that most strongly benefit from UHF, as well as chapters with a focus on different application areas in anatomical, functional and metabolic imaging. Finally, several chapters highlight the neurological and psychiatric applications for which 7T has shown benefits. The book is aimed at scientists who develop MR techno...
Sessional Papers
"Report of the Dominion fishery commission on the fisheries of the province of Ontario, 1893", issued as vol. 26, no. 7, supplement.
Never Leave Me (Waters of Time Book #2)
In the last stages of a genetic disease, Ellen Creighton has decided to live out her remaining days at the estate of her longtime friend Harrison Burlington. Harrison cares deeply for Ellen, but as a wheelchair-bound paraplegic, he's never allowed himself to get serious in a relationship. However, he's desperately trying to save her by finding the holy water that is believed to heal any disease. When he locates two flasks, Ellen refuses to drink one of them because she believes the holy water killed her sister and father. In an effort to convince her to take it, Harrison ingests the contents first, and when Ellen witnesses the effects, she can no longer deny the power of the substance in the bottles. Dangerous criminals are also seeking the holy water, and Ellen soon learns they will go to any lengths to get the powerful drug--including sending her back into the past to find it for them. Bestselling and award-winning author Jody Hedlund plunges you into the swiftly flowing river of history in a race against the clock in this breathtaking, emotional second Waters of Time story.
Proof of Heaven
A mother’s faith, a child’s courage, a doctor’s dedication—a moving and thought-provoking tale of hope, love, and family He might be young, but Colm already recognizes the truth: that he’s sick and not getting better. His mother, Cathleen, fiercely believes her faith will protect her ailing son, but Colm is not so sure. With a wisdom far beyond his years, Colm has come to terms with his probable fate, but he does have one special wish. He wants to meet his father who abandoned his beloved mother before Colm was born. But the quest to find the dying boy’s missing parent soon becomes a powerful journey of emotional discovery—a test of belief and an anxious search for proof of heaven. A magnificent debut novel, Mary Curran Hackett’s Proof of Heaven is a beautiful and unforgettable exploration of the power of love and the monumental questions of life, death, and the afterlife.
Typewriter in the Sky
Modern man Mike de Wolf gets stranded in a pirate adventure being written by his friend Horace Hackett and finds himself fighting for his life as the villainous Miguel de Lobo, while trying to figure out how to extricate himself from Horace's fatal plot.
Women in Colonial Latin America, 1526 to 1806
"This outstanding collection makes available for the first time a remarkable range of primary sources that will enrich courses on women as well as Latin American history more broadly. Within these pages are captivating stories of enslaved African and indigenous women who protest abuse; of women who defend themselves from charges of witchcraft, cross-dressing, and infanticide; of women who travel throughout the empire or are left behind by the men in their lives; and of women’s strategies for making a living in a world of cross-cultural exchanges. Jaffary and Mangan's excellent Introduction and annotations provide context and guide readers to think critically about crucial issues related to the intersections of gender with conquest, religion, work, family, and the law." —Sarah Chambers, University of Minnesota
