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New Antibiotic Targets
This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. The book will provide laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.
Proceedings of 2009 Hales Lung Conference
The conference focused on pathophysiologic mechanisms, as well as diagnostic approaches to and care for patients with diffuse parenchymal disease. The conference brought together experts from various fields of research in pulmonary fibrosis, and allowed for cross-dissemination of ideas and experiences. 58 pages, perfect binding. Published by BioBitField, P.O. Box 1816, Ellicott City, MD 21041-1816, U.S.A. Table of Contents: 1. Sergei P. Atamas and Jeffrey D. Hasday.2009 Hales Lung Conference: Clinical and Pathophysiologic Aspects of Diffuse Parenchymal Lung Disease. 2. Richard P. Phipps, Geniece M. Lehmann, and Patricia J. Sime. Lung Fibrosis: the Impact of Fibroblast Diversity and Different...
University of Michigan Official Publication
Each number is the catalogue of a specific school or college of the University.
Inflammatory Processes:
In November 1998 many of the key leaders of new drug discovery for inflammatory diseases gathered at Hershey, Pennsylvania for the 9th International Conference of the Inflammation Research Association. The Conference was held over a five day period and provided a stimulating environment for the open exchange of important advances in basic inflammation research as well as new drug discovery and development. This book encompasses some of the highlights of several presentations made at the Conference. It contains some of the latest and important developments in the field of inflammation research. Topics include the status of eotaxin and chemokines in asthma and allergy, signal transduction and regulation of diverse mediators such as the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as regulators of AP-1, macrophage metalloproteinases, lymphotoxin and further insights into the role of MCP-1 in disease. Also discussed are drug targets in rheumatoid and osteoarthritis, fibrotic diseases,...
Skin
We expose it, cover it, paint it, tattoo it, scar it, and pierce it. Our intimate connection with the world, skin protects us while advertising our health, our identity, and our individuality. This dazzling synthetic overview is a complete guidebook to the pliable covering that makes us who we are. Skin: A Natural History celebrates the evolution of three unique attributes of human skin: its naked sweatiness, its distinctive sepia rainbow of colors, and its remarkable range of decorations. Jablonski places the rich cultural canvas of skin within its broader biological context for the first time, and the result is a tremendously engaging look at us.
Interstitial Lung Disease
Deals with interstitial lung diseases and includes clinical, pathologic, radiologic and physiologic evaluation of the patient with ILD. This book covers a wide array of disorders, sarcoidosis, asbestosis, hypersensitivity pneumonitis, drug induced lung disease, connective tissue disease and pulmonary vasculitis, to name but a few.
Myeloid-Derived Suppressor Cells
Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive protocols to assess the role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume includes interesting protocols that address the Detection of myeloid-derived suppressor cells by flow cytometry, Determination of murine myeloid-derived suppressor cells by flow cytometry, Isolation of Myeloid-Derived Suppressor Cells (MDSC) from Endometriotic Mice Model and their Immunomodulatory Functions, Simple protocol for measuring CD11b+ GR-1+ (Ly6C+/Ly6G+) myeloid...
