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Environmental Vibrations and Transportation Geodynamics
This book includes keynote presentations, invited speeches, and general session papers presented at the 7th International Symposium on Environmental Vibration and Transportation Geodynamics (formerly the International Symposium on Environmental Vibration), held from October 28 to 30, 2016 at Zhejiang University, Hangzhou, China. It discusses topics such as the dynamic and cyclic behaviors of soils, dynamic interaction of vehicle and transportation infrastructure; traffic-induced structure and soil vibrations and wave propagation; soil-structure dynamic interaction problems in transportation; environmental vibration analysis and testing; vehicle, machine and human-induced vibrations; monitoring, evaluation and control of traffic induced vibrations; transportation foundation deformation and deterioration induced by vibration; structural safety and serviceability of railways, metros, roadways and bridges; and application of geosynthetics in transportation infrastructure. It is a valuable resource for government managers, scientific researchers, and engineering professionals engaged in the field of geotechnical and transportation engineering.
Asymptotic Statistics in Insurance Risk Theory
This book begins with the fundamental large sample theory, estimating ruin probability, and ends by dealing with the latest issues of estimating the Gerber–Shiu function. This book is the first to introduce the recent development of statistical methodologies in risk theory (ruin theory) as well as their mathematical validities. Asymptotic theory of parametric and nonparametric inference for the ruin-related quantities is discussed under the setting of not only classical compound Poisson risk processes (Cramér–Lundberg model) but also more general Lévy insurance risk processes. The recent development of risk theory can deal with many kinds of ruin-related quantities: the probability of ...
Stochastic Volatility and Realized Stochastic Volatility Models
This treatise delves into the latest advancements in stochastic volatility models, highlighting the utilization of Markov chain Monte Carlo simulations for estimating model parameters and forecasting the volatility and quantiles of financial asset returns. The modeling of financial time series volatility constitutes a crucial aspect of finance, as it plays a vital role in predicting return distributions and managing risks. Among the various econometric models available, the stochastic volatility model has been a popular choice, particularly in comparison to other models, such as GARCH models, as it has demonstrated superior performance in previous empirical studies in terms of fit, forecasti...
Statistical Design and Analysis of Clinical Trials
Statistical Design and Analysis of Clinical Trials: Principles and Methods concentrates on the biostatistics component of clinical trials. Developed from the authors' courses taught to public health and medical students, residents, and fellows during the past 15 years, the text shows how biostatistics in clinical trials is an integration of many fu
Handbook of Statistics in Clinical Oncology
A compendium of cutting-edge statistical approaches to solving problems in clinical oncology, Handbook of Statistics in Clinical Oncology, Second Edition focuses on clinical trials in phases I, II, and III, proteomic and genomic studies, complementary outcomes and exploratory methods. Cancer Forum called the first edition a
Cluster Randomised Trials
Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects. In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on random...
Handbook of Statistics in Clinical Oncology, Third Edition
Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion of high-dimensional data and imaging techniques have become common practice, and statistical methods on how to analyse such data have been refined in this area. A compilation of statistical topics relevant to these new advances in cancer research, this third edition of Handbook of Statistics in Clinical Oncology focuses on the design and analysis of oncology clinical trials and transla...
Big Data Analytics in Oncology with R
Big Data Analytics in Oncology with R serves the analytical approaches for big data analysis. There is huge progressed in advanced computation with R. But there are several technical challenges faced to work with big data. These challenges are with computational aspect and work with fastest way to get computational results. Clinical decision through genomic information and survival outcomes are now unavoidable in cutting-edge oncology research. This book is intended to provide a comprehensive text to work with some recent development in the area. Features: Covers gene expression data analysis using R and survival analysis using R Includes bayesian in survival-gene expression analysis Discusses competing-gene expression analysis using R Covers Bayesian on survival with omics data This book is aimed primarily at graduates and researchers studying survival analysis or statistical methods in genetics.
Statistical Methods for Imbalanced Data in Ecological and Biological Studies
This book presents a fresh, new approach in that it provides a comprehensive recent review of challenging problems caused by imbalanced data in prediction and classification, and also in that it introduces several of the latest statistical methods of dealing with these problems. The book discusses the property of the imbalance of data from two points of view. The first is quantitative imbalance, meaning that the sample size in one population highly outnumbers that in another population. It includes presence-only data as an extreme case, where the presence of a species is confirmed, whereas the information on its absence is uncertain, which is especially common in ecology in predicting habita...
Bioequivalence and Statistics in Clinical Pharmacology
Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how, and why these studies are performed as part of drug development; and demonstrates the methods using real world examples. Drawing on knowledge gained directly from working in the pharmaceutical industry, the authors set the stage by describing the general role of statistics. Once the foundation of clinical pharmacology drug development, regulatory appl...
