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In this ingenious study, Kathryn Rudy takes the reader on a journey to trace the birth, life and afterlife of a Netherlandish book of hours made in 1500. Image, Knife, and Gluepot painstakingly reconstructs the process by which this manuscript was created and discusses its significance as a text at the forefront of fifteenth-century book production, when the invention of mechanically-produced images led to the creation of new multimedia objects. Rudy then travels to the nineteenth century to examine the phenomenon of manuscript books being pillaged for their prints and drawings: she has diligently tracked down the dismembered parts of this book of hours for the first time. Image, Knife, and ...
It is a day when everything aches and nails are raining from the sky. Anna's mother has died. Anna and her father are making their way to the funeral. But along the way they talk -- capturing memories, asking hard questions, picturing what heaven might be like. Anna's imagination leads both of them on a journey that, by the end, might just offer a certain sort of peace. With captivating artwork and text that is at times whimsical, at times haunting, this profound book will make a perfect companion for readers who are wrestling with their own questions about life's mysteries.
Garmann makes friends with Johanna, the twin sister of the girl who torments him at school, when they discover that they both love adventures and talking about outer space.
Visions of Savage Paradise is the first major book-length study of seventeenth-century Dutch artist Albert Eckhout to be published in nearly seventy years. Eckhout, who was court painter to the colonial governor of Dutch Brazil, created life-size paintings of Amerindians, Africans, and Brazilians of mixed race in support of the governor’s project to document the people and natural history of the colony. In this study, Rebecca Parker Brienen provides a detailed analysis of Eckhout’s works, framing them with discussions of both their colonial context and contemporary artistic practices in the Dutch republic.
Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managi...
The classic medical text known as Gray’s Anatomy is one of the most famous books ever written. Now, on the 150th anniversary of its publication, acclaimed science writer and master of narrative nonfiction Bill Hayes has written the fascinating, never-before-told true story of how this seminal volume came to be. A blend of history, science, culture, and Hayes’s own personal experiences, The Anatomist is this author’s most accomplished and affecting work to date. With passion and wit, Hayes explores the significance of Gray’s Anatomy and explains why it came to symbolize a turning point in medical history. But he does much, much more. Uncovering a treasure trove of forgotten letters an...
Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death can progress through connections. Accordingly, knowing how the various parts of the brain are interconnected to form functional systems is a prerequisite for properly understanding data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It focuses on human and primate data in the context of brain circuitry disorders, which are so common in neurological practice. In addition, numerous clinical cases are presented to demonstrate how normal brain ci...
Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.
This book traces the origins of the German welfare state. The author, formerly director at the Max-Planck-Institute for European Legal History, Frankfurt, provides a perceptive overview of the history of social security and social welfare in Germany from early modern times to the end of World War II, including Bismarck’s pioneering introduction of social insurance in the 1880s. The author unravels “layers” of social security that have piled up in the course of history and, so he argues, still linger in the present-day welfare state. The account begins with the first efforts by public authorities to regulate poverty and then proceeds to the “social question” that arose during the 19th-century Industrial Revolution. World War I had a major impact on the development of social security, both during the war and after, through the exigencies of the war economy, inflation and unemployment. The ruptures as well as the continuities of social policy under National Socialism and World War II are also investigated.