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This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.
1. Epidemiology / Trishe Y.-M. Leong and Anthony S.-Y. Leong -- 2. Liver terminology and anatomy / Steven M. Strasberg -- 3. Assessment of liver function / Darren V. Mann -- 4. Prevention / Michael C. Kew -- 5. Screening / Morris Sherman -- 6. Presentation and diagnosis / Dario Ribero, Gareth Morris-Stiff and Jean-Nicolas Vauthey -- 7. Tumor markers / John Y. H. Chan and Zhi Wang -- 8. Imaging / Simon S. M. Ho and Simon C. H. Yu -- 9. Pathology / Anthony S.-Y. Leong, Trishe Y.-M. Leong and Pongsak Wannakrairot -- 10. Molecular aspects / John Y. H. Chan, Kenneth K. H. Lee, Yiu-Loon Chui and Macus T. Kuo -- 11. Staging / Justin M. Burns and Frederick L. Greene -- 12. Selection of patients for ...
Proceedings of the NATO Advanced Study Institute, Hannover, Germany, July 13-25, 1979
Inter-Organellar Ca2+ Signaling in Health and Disease - Part A, Volume 362, the latest release in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review of Cell and Molecular Biology series - Updated release includes the latest information on the topic of Inter-Organellar Ca2+ Signaling in Health and Disease - Part A
Probabilistic and percentile/quantile functions play an important role in several applications, such as finance (Value-at-Risk), nuclear safety, and the environment. Recently, significant advances have been made in sensitivity analysis and optimization of probabilistic functions, which is the basis for construction of new efficient approaches. This book presents the state of the art in the theory of optimization of probabilistic functions and several engineering and finance applications, including material flow systems, production planning, Value-at-Risk, asset and liability management, and optimal trading strategies for financial derivatives (options). Audience: The book is a valuable source of information for faculty, students, researchers, and practitioners in financial engineering, operation research, optimization, computer science, and related areas.
Confidently sign out your most complex and challenging cases with the updated edition of Differential Diagnosis in Surgical Pathology. Widely used by residents and practicing pathologists alike, this comprehensive medical reference provides brief, bulleted descriptions of both common and rare disorders, integrating excellent illustrative examples of the pathology with selected references. It's the perfect go-to resource to have by your microscope! Quickly access essential information through concise, bulleted text; a consistent approach to diagnosis and interpretation; and a comprehensive yet manageable size. Formulate an accurate diagnosis with coverage of all of the relevant ancillary diag...
Widely used by residents, fellows, and practicing pathologists around the world, Gattusso's Differential Diagnosis in Surgical Pathology provides a user-friendly road map to the main criteria to consider in order to differentiate between a variety of potential diagnoses that all have a very similar appearance. This comprehensive guide helps you make informed decisions for even your most complex and challenging cases, presenting a comprehensive differential diagnosis list and comparisons for every entity discussed. The 4th Edition brings you fully up to date with updated diagnostic techniques, new classifications, and new content throughout—perfect for quick reference at every microscope in...
Differential Diagnosis in Surgical Pathology, 2nd Edition, by Paolo Gattuso, MD, Vijaya B. Reddy, MD, Odile David, MD, and Daniel J. Spitz, MD, is skillfully designed to help you confidently sign out your most complex and challenging cases. Covering a complete range of tumors and tumor-like conditions in all organ systems, it provides a user-friendly road map to the main criteria you should consider in order to differentiate between a variety of potential diagnoses that all have a very similar appearance. Over 1,350 new full-color macro- and microphotographs provide a realistic basis for comparison to what you see under the microscope. Quick checklists cover all diagnostic possibilities to m...