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The Centers for Disease Control and Prevention of the United States has deemed extended-spectrum β-lactamases (ESBLs)-producing Enterobacterales and multidrug-resistant (MDR) Pseudomonas aeruginosa as serious threats and carbapenem-resistant (CR) Enterobacterales (CRE) and CR Acinetobacter as urgent threats. Due to the prevalent drug resistance of these strains and lack of antimicrobial alternatives, the treatment of infections caused by these MDR Gram-negative pathogens rely on tigecycline, polymyxins (colistin and polymyxin B) or new β-lactam/β-lactamase inhibitor combinations (such as ceftazidime-avibactam, CAZ/AVI). However, the critically ill patients with antimicrobial infection are associated with high mortality. Hence, the prevalence and optimal therapy for critically ill patients with antimicrobial resistance are worth further study.
The School of Journalism at Columbia University has awarded the Pulitzer Prize since 1917. Nowadays there are prizes in 21 categories from the fields of journalism, literature and music. The Pulitzer Prize Archive presents the history of this award from its beginnings to the present: In parts A to E the awarding of the prize in each category is documented, commented and arranged chronologically. Part F covers the history of the prize biographically and bibliographically. Part G provides the background to the decisions.
Over the course of more than three centuries of Romanov rule in Russia, foreign visitors and residents produced a vast corpus of literature conveying their experiences and impressions of the country. The product of years of painstaking research by one of the world’s foremost authorities on Anglo-Russian relations, In the Lands of the Romanovs is the realization of a major bibliographical project that records the details of over 1200 English-language accounts of the Russian Empire. Ranging chronologically from the accession of Mikhail Fedorovich in 1613 to the abdication of Nicholas II in 1917, this is the most comprehensive bibliography of first-hand accounts of Russia ever to be published...