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Free Radicals in Biology, Volume III reviews diverse topics in free radical biology and relates the results of chemical and biochemical investigations to clinical situations. It attempts to bridge the gap between chemical investigations and the medical applications and implications of free radical reactions. Topics covered range from radiation chemistry to biochemistry, biology, and medicine. Comprised of seven chapters, this volume begins with a general introduction to the technique of radiation chemistry; the thermodynamics and kinetic factors that need be considered; the use of pulse radiolysis and flow techniques; and the application of these methods to free radicals of biological intere...
Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and th...
Free Radicals in Biology, Volume II is a nine-chapter text that describes the complexities in the chemical and physical behavior of free radicals. After briefly providing an overview of the biology of pyridinyl radicals, this book goes on discussing the role of glutathione in the cell and the reactions of single oxygen and its role in photochemical smog and in cellular chemistry. These topics are followed by a discussion on the production of free radicals from dry tissue. The subsequent chapters describe some of the key reactions in photochemical smog, including reaction studies by computer simulation, as well as the specific reactive materials that are present in smog. These chapters also look into the chemistry of nitrogen oxides and ozone, which are some of the most important reactions in photochemical smog. The concluding chapters explore the radiation damage to proteins and radiation protection and radical reactions produced by radiation in nucleic acids. Chemists, biologists, and physicists will find this text invaluable.
The term "soil health" refers to the functionality of a soil as a living ecosystem capable of sustaining plants, animals, and humans while also improving the environment. In addition to soil health, the environment also comprises the quality of air, water, vegetation, and biota. The health of soil, plants, animals, people, and the environment is an indivisible continuum. One of the notable ramifications of the Anthropocene is the growing risks of decline in soil health by anthropogenic activities. Important among these activities are deforestation, biomass burning, excessive soil tillage, indiscriminate use of agrochemicals, excessive irrigation by flooding or inundation, and extractive farm...
Free Radicals in Biology, Volume 1, provides an introduction to some of the basic concepts of free radical biology. The book emerged from the President's Symposium of the American Society for Experimental Pathology held in Atlantic City in April 1970. The book's opening chapter introduces a mechanistic view of free radical reactions using examples from biological systems. This is followed by a discussion of autoxidative damage to lipids in membranes. Some of the special chemistry of lipid oxidation are presented, and a number of novel ideas are suggested. The third chapter deals with the uses of electron-spin resonance in biology. Spin labeling is also discussed, which is one of the most useful methods of probing the chemical and physical environment of molecules in cells. The remaining chapters cover free radicals which occur in photosynthesis and the importance of the enzyme, superoxide dismutase. The study of the occurrence and reactions of this enzyme provides an important and extensive body of data clearly pointing to the significance of free radicals in cellular chemistry.
Free Radicals in Biology, Volume VI covers the significant biological implications of arachidonic acid chemistry in free radical biology. This 11-chapter volume explores the biochemistry of the prostaglandins, leukotrienes, and other products from arachidonic acid. The introductory chapters describe the chemistry of the eicosanoids; the structures of prostaglandin and leukotriene compounds; the role of lipid hydroperoxides in controlling prostaglandin biosynthesis; and the oxidation of xenobiotics during prostaglandin H biosynthesis. The discussion then shifts to the effects of the so-called fatty acid paradoxes on cell proliferation, tumorigenesis, and metastasis, followed by chapters on ar...