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Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.
This volume takes a fresh and innovative approach to the history of ideas of work, concerning perceptions, attitudes, cultures and representations of work throughout Antiquity and the medieval and early modern periods. Focusing on developments in Europe, the contributors approach the subject from a variety of angles, considering aspects of work as described in literature, visual culture, and as perceived in economic theory. As well as external views of workers the volume also looks at the meaning of work for the self-perception of various social groups, including labourers, artisans, merchants, and noblemen, and the effects of this on their self-esteem and social identity. Taking a broad chronological approach to the subject provides readers with a cutting-edge overview of research into the varying attitudes to work and its place in pre-industrial society.
It’s 1918. The outcome of the First World War is still in the balance. Germany’s submarines have failed to force Britain to the negotiation table. Something else must be tried. The 27,000 ton battle cruiser Hindenburg, Germany’s latest and most powerful, is dispatched to attack the Allied convoys. Her Prussian captain, Rupprecht Körner, faces a daunting task. His lone ship must break out into the Atlantic, avoiding contact with the massive British fleet, and journey even as far as America to find her prey. As well as coping with the North Atlantic weather and enemy warships, Körner must keep his ship’s coal bunkers replenished. Even if he is able to find targets for his big guns - no simple task in the vast ocean - he still has to get his ship and crew safely back to Germany. The odds seem stacked against him. He needs to succeed; Germany needs him to succeed.
Matt Erlin considers books and the culture around books during this period, focusing specifically on Germany where literature, and the fine arts in general, were the subject of soul-searching debates over the legitimacy of luxury.
Algorithmic and Aesthetic Literacy is a selection of texts aiming to extend current understandings of algorithmic and aesthetic literacy. The volume presents a wide array of transdisciplinary perspectives on computational and aesthetic practices and thinking. Drawing on computer and educational science, artistic research, designing and crafting, this collection delves deeply into societal and educational challenges in the wake of the digital transformation. The volume brings together diverse approaches and viewpoints to stimulate dialogue and awareness of the manifold ways in which algorithmic processes have become part of our lives. By extending our ability to respond to a data-driven world in creative and non-habitual ways, we will be better equipped to re-imagine and shape our collective future as meaningful and fulfilling.
Theareaofgraphtransformationoriginatedinthelate1960sunderthename “graph grammars” – the main motivation came from practical considerations concerning pattern recognition and compiler construction. Since then, the list of areas which have interacted with the development of graph transformation has grown impressively. The areas include: software speci?cation and development, VLSI layout schemes, database design, modeling of concurrent systems, m- sively parallel computer architectures, logic programming, computer animation, developmentalbiology,musiccomposition,distributedsystems,speci?cationl- guages, software and web engineering, and visual languages. As a matter of fact, graph transfo...
Published in Association with the German Historical Institute, Washington, D.C. Hitler's autobahn was more than just the pet project of an infrastructure-friendly dictator. It was supposed to revolutionize the transportation sector in Germany, connect the metropoles with the countryside, and encourage motorization. The propaganda machinery of the Third Reich turned the autobahn into a hyped-up icon of the dictatorship. One of the claims was that the roads would reconcile nature and technology. Rather than destroying the environment, they would embellish the landscape. Many historians have taken this claim at face value and concluded that the Nazi regime harbored an inbred love of nature. In this book, the author argues that such conclusions are misleading. Based on rich archival research, the book provides the first scholarly account of the landscape of the autobahn.
Drawing on cultural, social, and environmental history, as well as the histories of science and medicine, this book shows how, amidst a growing reaction against exotic imports -- whether medieval spices like cinnamon or new American arrivals like chocolate and tobacco -- early modern Europeans began to take inventory of their own "indigenous" natural worlds.
In The Shock of Recognition, Lewis Pyenson uses a method called Historical Complementarity to identify the motif of non-figurative abstraction in modern art and science. He identifies the motif in Picasso’s and Einstein’s educational environments. He shows how this motif in domestic furnishing and in urban lighting set the stage for Picasso’s and Einstein’s professional success before 1914. He applies his method to intellectual life in Argentina, using it to address that nation’s focus on an inventory of the natural world until the 1940s, its adoption of non-figurative art and nuclear physics in the middle of the twentieth century, and attention to landscape painting and the wonder of nature at the end of the century.
"This book evaluated the incorporation of technology into educational processes reviewing topics from primary and secondary school to higher education, from Second Life to wiki technology, from physical education to cultural learning"--Provided by publisher.