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Statistical Methods for Disease Clustering
  • Language: en
  • Pages: 240

Statistical Methods for Disease Clustering

This book is intended to provide a text on statistical methods for detecting clus ters and/or clustering of health events that is of interest to ?nal year undergraduate and graduate level statistics, biostatistics, epidemiology, and geography students but will also be of relevance to public health practitioners, statisticians, biostatisticians, epidemiologists, medical geographers, human geographers, environmental scien tists, and ecologists. Prerequisites are introductory biostatistics and epidemiology courses. With increasing public health concerns about environmental risks, the need for sophisticated methods for analyzing spatial health events is immediate. Further more, the research area...

Randomization, Masking, and Allocation Concealment
  • Language: en
  • Pages: 301

Randomization, Masking, and Allocation Concealment

  • Type: Book
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  • Published: 2017-10-30
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  • Publisher: CRC Press

Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly. Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization ...

Clinical Trial Data Analysis Using R and SAS
  • Language: en
  • Pages: 385

Clinical Trial Data Analysis Using R and SAS

  • Type: Book
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  • Published: 2017-06-01
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  • Publisher: CRC Press

Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it ...The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."—Journal of Statistical Software Clinical Trial Data Analysis Using R and SAS, Second Edition provides a thorough presentation of biostatistical analyses of clinical trial data with step-by-step implementations using R and SAS. The book’s practical, detailed approach d...

Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials
  • Language: en
  • Pages: 255

Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials

  • Type: Book
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  • Published: 2019-03-20
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  • Publisher: CRC Press

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these st...

Quantitative Methods for HIV/AIDS Research
  • Language: en
  • Pages: 309

Quantitative Methods for HIV/AIDS Research

  • Type: Book
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  • Published: 2017-08-07
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  • Publisher: CRC Press

Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.

Mathematical and Statistical Skills in the Biopharmaceutical Industry
  • Language: en
  • Pages: 230

Mathematical and Statistical Skills in the Biopharmaceutical Industry

  • Type: Book
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  • Published: 2019-07-15
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  • Publisher: CRC Press

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development. It was written to share a quintessence of the authors’ experiences acquired during many years of relevant work in the biopharmaceutical industry. The book will be useful will be useful for biopharmaceutical industry statisticians at different seniority levels and for graduate students who consider a biostatistics-related career in this industry. Features: Describes a system of principles for pragmatic problem solving in clinical drug development. Discusse...

Scan Statistics
  • Language: en
  • Pages: 410

Scan Statistics

Scan statistics is currently one of the most active and important areas of research in applied probability and statistics, having applications to a wide variety of fields: archaeology, astronomy, bioinformatics, biosurveillance, molecular biology, genetics, computer science, electrical engineering, geography, material sciences, physics, reconnaissance, reliability and quality control, telecommunication, and epidemiology. Filling a gap in the literature, this self-contained volume brings together a collection of selected chapters illustrating the depth and diversity of theory, methods and applications in the area of scan statistics.

Cluster Randomised Trials
  • Language: en
  • Pages: 425

Cluster Randomised Trials

  • Type: Book
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  • Published: 2017-07-06
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  • Publisher: CRC Press

Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects. In the time since the publication of the first edition, the use of cluster randomised trials (CRTs) has increased substantially, which is reflected in the updates to this edition. There are greatly expanded sections on random...

ONR Far East Scientific Bulletin
  • Language: en
  • Pages: 482

ONR Far East Scientific Bulletin

  • Type: Book
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  • Published: 1981
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  • Publisher: Unknown

description not available right now.

Biometrics
  • Language: en
  • Pages: 716

Biometrics

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

Emphasizes the role of statistics and mathematics in the biological sciences.