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The Ageing Immune System and Health
The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health.
Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases
Key Features Outlines therapies and techniques for HSCT for autoimmune diseases, and d Discusses its the advantages of HSCT over conventional therapies Reviews the entire process of stem cell therapy from harvest and ethics to indications of efficacy.
Revisiting the Metastatic Cascade: Putting Myeloid Cells Into Context
description not available right now.
Chemical Skin Injury
This book provides an up-to-date, compact but comprehensive review of chemical skin injuries, differentiating them from thermal skin burns. After an introductory chapter on the history of chemical skin injuries and the scope of the problem, the anatomy, histology, physiology, and immunology of normal skin are described. Mechanisms involved in chemical penetration of normal skin are explained, and the effects of damaged skin on chemical penetration are analyzed. The remainder of the book discusses a variety of clinically relevant aspects, such as the different forms of chemical skin injury, including injuries that arise during skin peeling or due to hair products; preventive measures; emergency treatment; rinsing therapy; medical and surgical treatment; and the importance of providing relevant information to workers. The role of predictive toxicology is also considered.
The Impact of Immunosenescence and Senescence of Immune Cells on Responses to Infection and Vaccination
description not available right now.
Detective Esqueleto: Jugando con fuego
Jugando con Fuego es la segunda novela protagonizada por Skulduggery, el detective esqueleto con poderes mágicos y su ayudante de 13 años, Valquiria Caín. La lucha contra las fuerzas del Mal prosigue y, en esta ocasión, tendrán que medir sus fuerzas contra el Barón Vengues. ¿Podrán impedir sus malvados planes? Las trepidantes peripecias de este original detective nos harán pasar muy buenos momentos.
Detective Esqueleto: La invocadora de la muerte
Los Nigromantes ya no necesitan a Valquiria, y esto es algo bueno, muy bueno. Aunque... solo hay una pega. Y es que la razón por la que los nigromantes no necesitan a nuestra protagonista es que ya han encontrado a la persona capaz de difuminar las frontera entre la vida y la muerte. Y esto es algo malo, muy malo...Así que, si como el Detective Esqueleto y Valquiria, creíais que ya habíais visto todo, estabais equivocados. Muy equivocados.
Detective esqueleto: Ataduras mortales [Skulduggery Pleasant]
Valquiria conoce su nombre verdadero. Ella es Oscuretriz y -si no hace nada por remediarlo- matará a sus padres. De hecho, acabará con toda la humanidad. Pero confesarle eso a Skulduggery es muy duro, así que tendrá que actuar por su cuenta, y dejarse morir, para sellar su corazón. Mientras tanto, un mago que vomita arañas conspira contra ellos, dos zombis quieren regresar a la vida, un asesino con el poder de hacer estallar los huesos los persigue y un Vestigio anda suelto. ¿Qué más puede ocurrir?
Detective Esqueleto: Días oscuros
Días oscuros es la cuarta novela protagonizada por Skulduggery Pleasant y su ayudante de 13 años, Valquiria Caín. La lucha contra las fuerzas del Mal prosigue pero, en esta ocasión, el detective esqueleto está perdido en una dimensión paralela y sus amigos tendrán que utilizar su calavera para traerlo de vuelta. Y al mismo tiempo... asesinos vengativos, zombis sedientos de sangre, vampiros neonatos, detectives corruptos y algunos monstruos más harán todo lo posible para desbaratar sus planes. Un libro divertido, trepidante y original que no deja indiferente.
The Aging Immune System and Health
The world population presents an increased percentage of individuals over 65 years old and the fastest growing subgroup is over 85 years old. The increase in life expectancy observed in the last century has not been synonymous with extra years lived in good health (disability-free years). Population studies have shown that as individuals age, they can present a great heterogeneity of ability and health. Therefore, aging has been associated for some individuals with disabilities and hospitalizations. Deaths related to infectious pathogens are increased in the aging population mainly due to pneumonia and influenza whereas Cytomegalovirus, Epstein-Barr virus, among other viruses seem to contrib...
