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Molecular Players in iPSC Technology
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associated genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of iPSC technology, regenerative medicine, and therapeutics Covers the different key molecular players involved in iPSC formation, maintenance, expansion, and differentiation Is contributed by world-renowned experts in the field
HIV I: Molecular Biology and Pathogenesis: Clinical Applications
The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, ...
The Biology of Krüppel-like Factors
Kruppel-like factors (KLFs) are attracting great attention across a wide spectrum of biological sciences and medicine because of their remarkable biological potency and the diversity of roles they play in the physiological and pathological changes of cells and tissues. This book is a comprehensive compendium of the latest research on the molecular mechanisms of KLFs, describing their roles in transcriptional regulation, cellular differentiation and development, the pathogenesis of the liver and cardiovascular systems and cancer, and generation of ES cells and iPS cells. As the only concise treatise written to date by leading experts in the field, it serves as an authoritative review of this family of molecules and is an essential reference for all who are interested in KLFs. The book also explores the potential of KLFs as targets for novel therapeutics and diagnostics, and will be invaluable in those fields.
Nerve Blockade and Interventional Therapy
This book provides physicians practicing at pain management clinics with comprehensive explanations of interventional therapeutic procedures including nerve blockade, as well as pharmacotherapy. Interventional therapeutic procedures including nerve blockade are categorized by devices into landmark (“blind”), X-ray-guided, ultrasound-guided, CT-guided, MR-guided, and endoscopic techniques. In this book, each chapter introduces one type of nerve blockade procedure that involves several different devices. The authors describe the pros and cons of each technique and make recommendations for the best devices to use. This book will also help anesthesiologists and other physicians to improve their treatment techniques.
Handbook of Clinical Anaesthesia 3E
The Handbook of Clinical Anaesthesia has been completely updated for this new edition, providing trainee anaesthetists with a concise but comprehensive source of clinical information, and qualified anaesthetists with an indispensable aide. Written and edited by experts in the field, this compact but detailed text provides all the essential practical knowledge required by anaesthetists on co-existing medical conditions, operative procedures, and techniques. The handbook is presented in Parts 1 to 3. The first part covers Patient Conditions; the second part Surgical Procedures; and the third part Anaesthetic Factors. Each part is subdivided into sections on each organ system, and each section is divided into chapters. These chapters are in alphabetical order, and cover all common and rare conditions that anaesthetists will encounter within their practice.Trainees will find this book to be an excellent general guide, but in particular a provider of reliable information in preparation for examination as well as teaching clinical technique and practice.
Handbook of Clinical Anaesthesia, Fourth edition
Written and edited by experts in the field, the Handbook of Clinical Anaesthesia provides all the essential practical knowledge required by anaesthetists on co-existing medical conditions, operative procedures, and techniques. The fourth edition retains the concise and comprehensive nature of the third, giving readers all they need to know about each part of the FRCA syllabus in short, digestible, practical entries. The first part covers Patient Conditions; the second Surgical Procedures; and the third Anaesthetic Factors. Each part is subdivided into chapter on each organ system, and each chapter is divided into bite-sized entries. These are in alphabetical order, and cover all common and rare conditions that anaesthetists will encounter within their practice. Avoiding prolonged discussion and multiple references, this is the ideal book to ‘dip into’ either for specific advice or general education, providing quick and reliable information. This is the most thorough handbook to cover the entire FRCA syllabus in a consistent and instructive manner. It continues to be accessible and relevant to all anaesthetists from middle grade trainee up to consultant/specialist.
The Placenta, Fetomaternal Tolerance and Beyond: A Tribute to Sir Peter Medawar on the 60th Anniversary of his Nobel Prize
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Urological Cancer 2020
This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
Genetic Regulation of Placental Development, and Immunology
This work, the 11th Volume of Trophoblast Research series, comprises collected papers presented to the 13th Rochester Trophoblast Conference (Summer 1996), held for the first time at Banff, Alberta, Canada. This edited volume hopes to recreate the main scientific themes discussed at this meeting for the reader. Established in 1961, the Rochester Trophoblast Conference is the oldest international conference on the placenta, and it became a formal corporate member of the International Federation of Placental Associations at the Banff conference.
