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Alternative Splicing in Brain Function
Functional and structural intricacies of biological systems emerge from the complex nature of the genome. A key aspect of genome complexity can be attributed to the process of alternative splicing of precursor mRNA (or pre-mRNA), during which introns are removed and exons are selectively spliced together. This highly regulated process generates different mature mRNA transcripts from a single gene and is widespread throughout the eukaryotic evolution. The majority of the genes expressed in the mammalian central nervous system undergo extensive alternative splicing. Some genes can generate more than a thousand isoforms resulting in diverse proteoforms that can differ in their function, binding...
Chinese History
Endymion Wilkinson's bestselling manual of Chinese history has long been an indispensable guide to all those interested in the civilization and history of China. In this latest edition, now in a bigger format, its scope has been dramatically enlarged by the addition of one million words of new text. Twelve years in the making, the new manual introduces students to different types of transmitted, excavated, and artifactual sources from prehistory to the twentieth century. It also examines the context in which the sources were produced, preserved, and received, the problems of research and interpretation associated with them, and the best, most up-to-date secondary works. Because the writing of history has always played a central role in Chinese politics and culture, special attention is devoted to the strengths and weaknesses of Chinese historiography.
Modern Technologies in Materials, Mechanics and Intelligent Systems
Selected, peer reviewed papers from the 2014 4th International Conference on Intelligent System and Applied Material (GSAM 2014), August 23-24, 2014, Taiyuan, China
High Performance Computing
This book constitutes the refereed proceedings of the National Annual Conference on High Performance Computing, HPC 2012, held in Zhangjiajie, China, in October 2012. The 14 revised full papers presented were carefully reviewed and selected from 260 submissions. The papers address issues such as parallel architecture, GPU computing, resource scheduling, parallel algorithm, and performance evaluation.
Mathematical Olympiad In China (2021-2022): Problems And Solutions
In China, many excellent students in mathematics take an active part in various mathematical contests, and each year, the best six senior high school students are selected to form the IMO National Team to compete in the International Mathematical Olympiad. In the past ten years, China's IMO Team has achieved outstanding results — they won first place almost every year.The authors of this book are coaches of the China national team. They are Xiong Bin, Xiao Liang, Yu Hongbing, Yao Yijun, Qu Zhenhua, Li Ting, Ai Yinhua, Wang Bin, Fu Yunhao, He Yijie, Zhang Sihui, Wang Xinmao, Lin Tianqi, Xu Disheng, et al. Those who took part in the translation work are Chen Haoran and Zhao Wei.The materials of this book come from a series of two books (in Chinese) on Forward to IMO: a collection of mathematical Olympiad problems (2021-2022). It is a collection of problems and solutions of the major mathematical competitions in China. It provides a glimpse of how the China national team is selected and formed.
