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Traditionally, surgery, radiotherapy, chemotherapy and hormonal therapy have been used in clinical practice to treat cancer patients. However, these methods are either not completely tumor free or without collateral damage to health tissues. Therefore, tumor recurrence, partial remission, treatment side effect and poor tolerance in elderly patients, and lack of effective strategy to treat late-stage cancers have been the major hurdles faced by clinicians in health care. Although cancer immunotherapy including checkpoint blockade, CAR-T, oncolytic viruses, and recombinant cytokines has taken center stage in mainstream oncology because of its specifically targeting tumor cells without affecting surrounding normal cells, only a proportion of patients receiving treatment respond and others relapse after an initial response. Different tumor indications respond differently, and even in cancer types that respond, unresponsiveness are still observed. This resistance suggests that either lack of sufficient host recognition and immunity (intrinsic) or active immune suppression by tumor complex (acquired).
These are the proceedings of the International Conference on Design, Fabrication and Economy of Metal Structures held on 24-26 April 2013 in Miskolc, Hungary which contain 99 papers covering: Structural optimization Thin-walled structures Stability Fatigue Frames Fire Fabrication Welding technology Applications Steel-concrete composite Special problems The authors are from 23 different countries, ensuring that the themes covered are of worldwide interest and importance. The International Institute of Welding (IIW), the International Society of Structural and Multidisciplinary Optimization (ISSMO), the TÁMOP 4.2.1.B-10/2/KONV-2010-0001 project entitled “Increasing the quality of higher edu...
A compelling examination of the ultimate global commodity, blue and white porcelain, from kiln to consumers across the globe.
This book gathers selected papers from the Chinese Materials Conference 2018 (CMC2018) held in Xiamen City, Fujian, China, on July 12–16, 2018. The Chinese Materials Conference (CMC) is the Chinese Materials Research Society’s most important conference series and has been held annually since the early 1990s. The 2018 edition consisted of 32 domestic symposia, 2 international symposia and 1 international materials forum. This proceedings book covers the fields of powder metallurgy, advanced aluminum alloys, advanced magnesium alloys, superalloys, metal matrix composites, space materials science and technology, as well as nanoporous metal materials, and presents recent original research findings from more than 300 research groups at various universities and research institutes.
ICAME 2012 Selected, peer reviewed papers from the 2012 International Conference on Advances in Mechanics Engineering (ICAME 2012), August 3-5, 2012, Hong Kong
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This book gathers outstanding papers presented at the 17th Annual Conference of China Electrotechnical Society, organized by China Electrotechnical Society (CES), held in Beijing, China, from September 17 to 18, 2022. It covers topics such as electrical technology, power systems, electromagnetic emission technology, and electrical equipment. It introduces the innovative solutions that combine ideas from multiple disciplines. The book is very much helpful and useful for the researchers, engineers, practitioners, research students, and interested readers.
With contributed papers from the 2011 Materials Science and Technology symposia, this is a useful one-stop resource for understanding the most important issues in the processing and properties of advanced ceramics and composites. Logically organized and carefully selected, the articles cover the themes of the symposia: Innovative Processing and Synthesis of Ceramics, Glasses and Composites; Advances in Ceramic Matrix Composites; Solution-Based Processing of Materials; and Microwave Processing of Materials. A must for academics in mechanical and chemical engineering, materials and or ceramics, and chemistry.
The book is the volume of “Religious History in the Qing Dynasty” among a series of books of “Deep into China Histories”. The earliest known written records of the history of China date from as early as 1250 BC, from the Shang dynasty (c. 1600–1046 BC) and the Bamboo Annals (296 BC) describe a Xia dynasty (c. 2070–1600 BC) before the Shang, but no writing is known from the period The Shang ruled in the Yellow River valley, which is commonly held to be the cradle of Chinese civilization. However, Neolithic civilizations originated at various cultural centers along both the Yellow River and Yangtze River. These Yellow River and Yangtze civilizations arose millennia before the Shang...
This proceedings volume contains selected papers presented at the 2014 AASRI International Conference on Applied Engineering Sciences, held in Hollywood, LA, USA. Contributions cover the latest developments and advances in the field of Applied Engineering Sciences.