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Negative Affective States and Cognitive Impairments in Nicotine Dependence
Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions. The combination of clinical and preclinical ...
Anhedonia: Preclinical, Translational, and Clinical Integration
Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to dist...
The Neuroscience of You
From University of Washington professor Chantel Prat comes The Neuroscience of You, a rollicking adventure into the human brain that reveals the surprising truth about neuroscience, shifting our focus from what’s average to an understanding of how every brain is different, exactly why our quirks are important, and what this means for each of us. With style and wit, Chantel Prat takes us on a tour of the meaningful ways that our brains are dissimilar from one another. Using real-world examples, along with take-them-yourself tests and quizzes, she shows you how to identify the strengths and weakness of your own brain, while learning what might be going on in the brains of those who are unlik...
Translational Neuropsychopharmacology
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.
The Alchemy of Meth
Meth cooks practice late industrial alchemy—transforming base materials, like lithium batteries and camping fuel, into gold Meth alchemists all over the United States tap the occulted potencies of industrial chemical and big pharma products to try to cure the ills of precarious living: underemployment, insecurity, and the feeling of idleness. Meth fires up your attention and makes repetitive tasks pleasurable, whether it’s factory work or tinkering at home. Users are awake for days and feel exuberant and invincible. In one person’s words, they “get more life.” The Alchemy of Meth is a nonfiction storybook about St. Jude County, Missouri, a place in decomposition, where the toxic in...
Tag für Tag jünger
Man ist nie zu alt, um jünger zu werden Was hält uns jung? Und können wir uns gar verjüngen? Ja! Der Schlüssel dafür liegt in einer gesunden und leistungsfähigen Zellerneuerung. Wie wir unsere Zellen auf Trab halten und was uns fit, gesund und schön hält, erklären die Professorin für Frauenheilkunde und Geburtshilfe Marion Kiechle und die Fachjournalistin für Beauty & Health Julie Gorkow anhand neuester medizinischer Erkenntnisse. Tatsächlich können wir unsere Zellen fit halten – und mit dem richtigen Know-how über Ernährung, Bewegung, Hormone und unser inneres und äußeres Wohlbefinden sogar einen Verjüngungsprozess einleiten. Intelligente Anti-Aging-Strategien für Frauen ab 40!
Index of Patents Issued from the United States Patent Office
pt. 1. List of patentees.--pt. 2. Index to subjects of inventions.
Official Gazette of the United States Patent and Trademark Office
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