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This detailed book delves into the diverse techniques and applications to target, isolate, image, phenotype, and analyze tissue-resident and monocyte-derived macrophages. The contents aim to describe the current knowledge about macrophage development and function which forces the scientific field to move beyond the previously described M1/M2 macrophage paradigm to be able to dissect macrophage functions within their specific niches during health and disease. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and practical, Tissue-Resident Macrophages: Methods and Protocols provides scientists entering the macrophage field with information and tools that allow them to dive into the state-of-the-art methodology used in this vital field.
This book introduces the basics of cellular and molecular biology on a basic level including detailed explanations and examples. It lays the foundation for a systematic understanding of biology, which is essential in order to handle big data in biomedical research. Comprehension of what is measured, how it is measured and how to interpret results is a precondition for the development of novel therapies against diseases.Interdisciplinary research benefits from versatile approaches to generate and test hypotheses, which may lead to new discoveries. Therefore, it requires a new generation of biologists from diverse backgrounds - and they need this introduction.This book helps students and experts from e.g. computer science, informatics, mathematics, physics, and related fields or even if you are in sales and marketing and want to have a better understanding of the biology behind certain products.
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. - Informs and updates on all the latest developments in the field - Contributions from leading authorities and industry experts
Buku ini membahas tentang imunologi dengan lebih rinci dan mendalam sesuai dengan pengetahuan yang dibutuhkan dalam imunologi dasar. Pembahasan dalam tiap bab dan sub bab dirancang secara jelas dan memperhatikan perkembangan dalam imunologi namun tidak terlalu panjang. Referensi yang digunakan adalah referensi-referensi yang mutakhir sehingga banyak hal baru yang bisa dilihat pada buku ini. Referensi lama kami gunakan jika tidak ditemukan referensi yang berumur kurang dari lima tahun dan hasil penelitian pada referensi tersebut masih relevan dengan imunologi masa kini. Di dalam buku ini juga memuat bab khusus yang membahas integrasi imunologi dengan ajaran islam. Kesemua hal tersebut menurut hemat kami merupakan sisi baik dari buku ini.
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