Seems you have not registered as a member of localhost.saystem.shop!
You may have to register before you can download all our books and magazines, click the sign up button below to create a free account.
Immunoendocrinology in Health and Disease
One of the first comprehensive references dealing specifically with this new field of interdisciplinary research in medicine, Immunoendocrinology in Health and Disease offers a full scientific picture of where the immune and neuroendocrine systems intersect-placing current understanding of system components, mechanisms, and functions side by side w
The Amphipathic Helix
The Amphipathic Helix is a comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, mitochondrial targeting, peptide hormones, G proteins, T-cell recognition, DNA binding proteins, and antifreeze proteins. The book also includes general introductory material that defines amphipathic helices, discusses methods to identify amphipathic helical segments from the amino acid sequence of a protein, illustrates how amphipathic helices can be used in the de novo design of peptide and protein structures, and describes how these helices stabilize protein structures. There is also a section on techniques to determine helix orientation in a membrane environment using polarized attenuated total reflection infrared spectroscopy or solid state NMR spectroscopy. Recent developments on all these topics have been discussed by leading experts in this reference for researchers and students in biochemistry, biophysics, and pharmacology.
The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer
Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications.
Untranslatability Goes Global
This book promotes interdisciplinary dialogue about untranslatability and its implications within the context of globalization. It examines at the pragmatics of translation practice, the role of the translator’s voice and the translator as author in specific literary works, and case studies across a variety of genres and traditions across regions.
Autonomic Neuroimmunology
While it may appear that the nervous and immune systems exist as two separate entities, groundbreaking observations have positively identified anatomic connections between elements of the nervous system and cells of adaptive immunity. Building on this research, Autonomic Neuroimmunology presents a scientific discussion of the current understanding of these vital neuroimmunological interactions and their implications for normal psychology and disease states. Contributors document the cell biological mechanisms for the neuropeptide activation of mast cells, and analyze how one or more adrenergenic and peptidergic messengers modulate immunity. They also explain the pathways by which cholinergic factors may suppress immunological inflammation. The potential implications of organ system-selective neuroimmunology for host defense and diseases are thoroughly discussed for the skin, the intestines, the bladder, and the lungs. With modern neuroimmunology now firmly established as a scientific discipline, this volume supports this promising science as a pathway to novel diagnostic and therapeutic techniques for diseases of the neural, immune, and endocrine systems.
Sociocultural Studies and Implications for Science Education
The chapters included in this book address two major questions: what are some of the methodological and theoretical issues in sociocultural research in urban education and science education and what sort of questions do technological and virtual contexts raise for these types of research perspectives. The chapters build off Ken Tobin's personal history of sociocultural research in science education and as they do each chapter asks philosophical, sociological and/or methodological questions that inform our understanding of the challenges associated with conducting research in experiential and virtual contexts.
Signal Transduction Research Trends
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Allergy and Allergic Diseases
Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book's content is div...
The Palgrave Handbook of Women’s Political Rights
This Palgrave Handbook provides a definitive account of women’s political rights across all major regions of the world, focusing both on women’s right to vote and women’s right to run for political office. This dual focus makes this the first book to combine historical overviews of debates about enfranchising women alongside analyses of more contemporary efforts to increase women’s political representation around the globe. Chapter authors map and assess the impact of these groundbreaking reforms, providing insight into these dynamics in a wide array of countries where women’s suffrage and representation have taken different paths and led to varying degrees of transformation. On the eve of many countries celebrating a century of women’s suffrage, as well as record numbers of women elected and appointed to political office, this timely volume offers an important introduction to ongoing developments related to women’s political empowerment worldwide. It will be of interest to students and scholars across the fields of gender and politics, women’s studies, history and sociology.
