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Towards continued and affordable accessibility of innovative drugs: Sustainable development and efficient use of medicines
  • Language: en
  • Pages: 143

Towards continued and affordable accessibility of innovative drugs: Sustainable development and efficient use of medicines

The rising costs of medicines is a major burden for healthcare systems and is already limiting access to innovative treatments worldwide. Governments, healthcare providers and payers constantly try to improve the sustainability of drug development, production, pricing and use of medicines. The aim of this research topic is to identify strategies and policies that can facilitate sustainable development and use of medicines as well as practical solutions to improve their cost-effectiveness. For this topic, we are also interested in alternative pricing strategies and financial arrangements, requisite changes in regulatory and legal frameworks to support sustainability, the potential role of reg...

Bioscience - Lost in Translation?
  • Language: en
  • Pages: 314

Bioscience - Lost in Translation?

Medical innovation as it stands today is fundamentally unsustainable. There is a widening gap between what biomedical research promises and the impact that it is currently achieving, in terms of patient benefit and health system improvement. This book highlights the global problem of the ineffective translation of bioscience innovation into health system improvements and its consequences, analyses the underlying causative factors and provides powerful prescriptions for change to close the gap. It contrasts the progress in biomedicine with other areas of scientific and technological endeavour, such as information technology, in which there are faster and more reliable returns for society. The...

Assessment and Treatment of Sarcopenia and Frailty in the Setting of Personalized Internal Medicine
  • Language: en
  • Pages: 150

Assessment and Treatment of Sarcopenia and Frailty in the Setting of Personalized Internal Medicine

The recognition and implementation of personalized internal medicine is of the utmost importance for physicians, nurses, dieticians and other healthcare professionals engaged in clinics. The assessment of sarcopenia and frailty, in middle-aged patients, as an embodiment of treatment personalization, is essential in settings of acute and chronic disease, both in the hospital and in ambulatory settings. This book describes various practical tools for the assessment of sarcopenia and frailty, reviews relevant findings from the current professional literature, and suggests treatment modifications for frail patients.

WHO guideline on country pharmaceutical pricing policies
  • Language: en
  • Pages: 70

WHO guideline on country pharmaceutical pricing policies

In recent years, high prices of pharmaceutical products have posed challenges in high- and low-income countries alike. In many instances, high prices of pharmaceutical products have led to significant financial hardship for individuals and negatively impacted on healthcare systems' ability to provide population-wide access to essential medicines. Pharmaceutical pricing policies need to be carefully planned, carried out, and regularly checked and revised according to changing conditions. Strong, well-thought-out policies can guide well-informed and balanced decisions to achieve affordable access to essential health products. This guideline replaces the 2015 WHO guideline on country pharmaceutical pricing policies, revised to reflect the growing body of literature since the last evidence review in 2010. This update also recognizes country experiences in managing the prices of pharmaceutical products.

Praxishandbuch Tageskliniken
  • Language: de
  • Pages: 233

Praxishandbuch Tageskliniken

Der Autor zeigt Ihnen bei welchen Störungsbildern die Behandlung in einer Tagesklinik geeignet ist und informiert Sie , welche Therapien dabei sinnvoll sind und wie sie optimal in diesem Rahmen gestaltet werden können. Das Praxishandbuch Tageskliniken dient als Ratgeber auch rund um die Organisation einer Tagesklinik – von Mitarbeiterstruktur über Tagespläne und Entlassungsrituale bis zu den wirtschaftlichen Aspekten. Darüber hinaus kann Sie das Buch auch unterstützen, wenn es um das Festlegen einer weiterführenden Behandlung des Patienten geht. Tageskliniken gewinnen zunehmend an Bedeutung. Für viele Störungsbilder ist eine Tagesklinik die bessere Wahl, psychisch Erkrankte bleiben in ihrem gewohnten Umfeld, werden weniger stigmatisiert und können Erlerntes besser im Alltag erproben.

Oxford Textbook of Communication in Oncology and Palliative Care
  • Language: en
  • Pages: 457

Oxford Textbook of Communication in Oncology and Palliative Care

Communication is a core skill for medical professionals when treating patients. Cancer and palliative care present some of the most challenging clinical situations. This book provides evidence-based guidelines alongside case examples, tips, and strategies to achieve effective, patient-centred communication.

Litigation and Settlement in a Game with Incomplete Information
  • Language: en
  • Pages: 177

Litigation and Settlement in a Game with Incomplete Information

We investigate a two-person game of litigation and settlement with incomplete information on one side. So far, various theoretical attempts have been made to answer the question of why some people choose not to resolve their disputes and instead go to court and incur litigation costs, even if bargaining leaves room for both parties to fare better when avoiding the conflict. We can distinguish between games which focus on strategic elements like games with incomplete information (see, for example, P'ng (1983), Samuelson (1982) and Schweizer (1989» and decision-theoretic models neglecting strategic elements (see, for example, Landes (1971) and Gould (1973». The single-person decision theory ...

Production of Biologicals from Animal Cells in Culture
  • Language: en
  • Pages: 853

Production of Biologicals from Animal Cells in Culture

Production of Biologicals from Animal Cells in Culture reviews the state of the art in animal cell biotechnology, with emphasis on the sequence of events that occur when generating a biological from animal cells in culture. Methods that enable adjustment of nutrient feed streams into perfusion bioreactors so as to increase productivity are described. A number of issues are also addressed, such as the usefulness of the fingerprint method for cell characterization. Comprised of 135 chapters, this book begins with an overview of the problems and benefits of animal cell culture, followed by a discussion on the isolation of immortal murine macrophage cell lines. The reader is systematically intro...

Proceedings on 25th International Joint Conference on Industrial Engineering and Operations Management – IJCIEOM
  • Language: en
  • Pages: 548

Proceedings on 25th International Joint Conference on Industrial Engineering and Operations Management – IJCIEOM

This book presents the conference proceedings of the 25th edition of the International Joint Conference on Industrial Engineering and Operations Management. The conference is organized by 6 institutions (from different countries and continents) that gather a large number of members in the field of operational management, industrial engineering and engineering management. This edition of the conference had the title: THE NEXT GENERATION OF PRODUCTION AND SERVICE SYSTEMS in order to emphasis unpredictable and very changeable future. This conference is aimed to enhance connection between academia and industry and to gather researchers and practitioners specializing in operation management, industrial engineering, engineering management and other related disciplines from around the world.