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Contemporary Oral Medicine
This book, written by world authorities in the field, is a comprehensive, up-to-date guide to the specialty of Oral Medicine, which is concerned with the diagnosis, prevention, and predominantly non-surgical management of medically related disorders and conditions affecting the oral and maxillofacial region. The pathophysiology, clinical presentation, diagnostic evaluation, and treatment of all relevant diseases and disorders are described with the aid of a wealth of clinical cases and illustrations that enable the reader to appreciate the diversity and potential complexity of Oral Medicine. In addition to the wide-ranging coverage of oral conditions, separate sections are devoted to bone and cutaneous pathology and to orofacial pain and its management, in addition to dental sleep medicine. The clinician who treats Oral Medicine patients will find this book to be an excellent aid to optimal management grounded in a sound knowledge of basic science and the dental and medical aspects of each disorder. In addition, it will serve as an outstanding textbook for undergraduate and postgraduate students.
Contemporary Oral Oncology
This is the first of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume, on tumor biology, epidemiology, etiology, emerging role of cancer stem cells and prevention of oral cancer, opens by discussing oral carcinogenesis in general and the role of particular carcinogens and human papillomavirus. Global epidemiology and changes in disease prevalence are then addressed. Up-to-date information is provided on emerging cancer biomarkers, and the biologic basis of personalized therapy is explained. Histopathological feat...
Premalignant Conditions of the Oral Cavity
Oral squamous cell carcinoma (SCC) is the 13th commonest cancer worldwide, and the most common cancer in the Asian subcontinent due to the widespread habit of tobacco and betel nut chewing. Despite many advances in diagnosis and treatment, the survival statistics have only marginally improved. However our understanding of the disease process and transformation from pre-cancerous lesions of the oral mucosa to an invasive SCC cancer and their progression has expanded exponentially. There are many conditions of the oral mucosa that can progress to an invasive malignancy. A thorough understanding of these conditions is a prerequisite for all those involved in the management of the diseases of th...
Contemporary Issues in Head and Neck Cancer Management
While the management of head and neck cancer has evolved over the last few decades, there are still several challenges and unanswered questions that need solutions. This book is a small compilation of some topical aspects regarding head and neck cancer treatment, including the etiology of HPV-positive oropharyngeal cancers and risk factors in the young population, the challenge of surgical margin definition and the perennial problem of systemic treatment due to distant metastases. Radiobiological aspects are also covered through the Rs of radiotherapy, with a couple of chapters being dedicated to radioresistance and tumour microenvironment. Contemporary Issues in Head and Neck Cancer Management comes as an addition to the existing literature that aims to tackle this radiobiologically challenging tumour.
Fungal Immunology:
A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.
Regenerative Approaches in Dentistry
This book provides evidence-based information in the field of regenerative dentistry discussing the most recent advances, current clinical applications, limitations and future directions. The coverage encompasses the regeneration of alveolar bone, the dentine-pulp complex, enamel, the periodontium and other tissues associated with the oral cavity. A full description is provided of regenerative approaches in dentistry including regenerative endodontics and tooth repair, regenerative periodontics, regenerative assisted orthodontics, regenerative approaches in oral medicine, and dental tissue derived stem cells and their potential applications. The book is written by an international team of leading experts. It will be beneficial for students, practitioners and researchers in the fields of endodontics, periodontics and implantology.
Next Generation Sequencing in Cancer Research, Volume 2
Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable cancer treatment plan and potential cure is more optimistic now with the unfolding of the cancer genome. The collective knowledge of how to leverage next generation sequencing in cancer research is paving the way. The important information provided in this volume will move the field forward in developing novel targeted cancer therapies.
Translational Systems Medicine and Oral Disease
Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland disease...
Development of Oral Cancer
This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students.
Teaching, Learning, and Leading With Computer Simulations
Computer simulation, a powerful technological tool and research-proven pedagogical technique, holds great potential to enhance and transform teaching and learning in education and is therefore a viable tool to engage students in deep learning and higher-order thinking. With the advancement of simulation technology (e.g., virtual reality, artificial intelligence, machine learning) and the expanded disciplines where computer simulation is being used (e.g., data science, cyber security), computer simulation is playing an increasingly significant role in leading the digital transformation in K-12 schools and higher education institutions, as well as training and professional development in corpo...
