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Role of congestion in heart failure: From bench to clinical practice
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Novel Therapeutic Targets and Emerging Treatments for Fibrosis
For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is the culmination of both excess extracellular matrix deposition due to ongoing or severe injury, and a failure to regenerate. An inadequate wound repair process ultimately results in organ failure through a loss of function, and is therefore a major cause of morbidity and mortality in disease affecting both multiple and individual organs. Whilst the pathology of fibrosis and its significance are well understood, until recently we have known little about its molecular regulati...
Reducing the Harm of Medication - Recent Trends in Pharmacovigilance, Volume II
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Anales de la Real Academia Nacional de Medicina - 2004 - Tomo CXXI - Cuaderno 1
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Applied Computer Sciences in Engineering
This volume constitutes the refereed proceedings of the 8th Workshop on Engineering Applications, WEA 2021, held in Medellín, Colombia, in October 2021. Due to the COVID-19 pandemic the conference was held in a hybrid mode. The 33 revised full papers and 11 short papers presented in this volume were carefully reviewed and selected from 127 submissions. The papers are organized in the following topical sections: computational intelligence; bioengineering; Internet of Things (IoT); optimization and operations research; engineering applications.
Pathobiochemistry of Metabolic Disorders
Pathobiochemistry means biochemistry of disease. In the curriculum of medical studies it may serve as a useful and highly enjoyable “bridge” between the basic science of the first years, and the clinical training later. Practical limitations dictate that from a vast area of human pathology a careful selection of topics must be made. The eleven chapters of this book deal with the basics of acid-base balance disorders, inflammation, reactive oxygen species and antioxidant defense, non-enzymatic glycations, atherosclerosis, metabolic syndrome, ischemia/reperfusion of the heart, protein misfolding disorders, ageing, and consequences of alcohol abuse. The selection covers some pathogenetic processes behind several important medical problems of the present. Further, it more or less implicitly points to the inner causes of diseases. The inner maintenance of body structural and chemical integrity is costly and has its limits that regularly get exceeded, which is the ultimate reason for ageing and contributes to many, often also age-related, civilization diseases.
Advances in Artificial Intelligence
This book constitutes the refereed proceedings of the 16th Conference of the Spanish Association for Artificial Intelligence, CAEPIA 2015, held in Albacete, Spain, in November 2015. The 31 revised full papers presented were carefully selected from 175 submissions. The papers are organized in topical sections on Bayesian networks and uncertainty modeling; fuzzy logic and soft computing; knowledge representation, reasoning, and logic; intelligent systems and environment; intelligent Web and recommender systems; machine learning and data mining; metaheuristics and evolutionary computation; and social robotics.
