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Role of Nrf2 in Disease: Novel Molecular Mechanisms and Therapeutic Approaches
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Diabetic Nephropathy
Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy. The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy. The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines. Features: Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy Provides novel information on various pharmacological interventions of diabetic nephropathy
Animal Bioethics
Animal Bioethics is an important reference work for students of biomedicine and related fields, scientific researchers, and members of organizations for the protection of animal rights and welfare. The philosophical background of monistic and dualistic concepts of the human-animal relationship is considered in detail. Experimental models in drug development and pain testing are analyzed, and the translational aspect of in vivo experiments discussed. One chapter is dedicated to neuroethics, taking into account the importance of animal experiments for examining brain function. Finally, an overview of modern legislation related to animal experiments is given, the ethical basis of the principles of Good Laboratory Practice is assessed, and the importance of animal bioethics for writing scientific projects is shown.
Dark Calories
'Mind-blowing - will change the way you eat forever.' Davinia Taylor, Sunday Times number one bestselling author of It's Not a Diet and Hack Your Hormones Did you know that eating a single large serving of french fries cooked in vegetable oil delivers the toxicity of smoking 24 cigarettes? Somewhere between 25 and 45 percent of the calories in your diet are likely coming from a substance most people know nothing about, a seemingly innocuous oil with no colour or flavour, that is quite possibly more harmful to your health than smoking cigarettes. Whether you shop at a health food store or a discount supermarket, the ingredient labels on most products in your kitchen right now may contain the ...
Worldwide Commonalities and Challenges in Information Literacy Research and Practice
This book constitutes the refereed proceedings of the European Conference on Information Literacy, ECIL 2013, held in Istanbul Turkey, in October 2013. The 73 revised full papers presented together with two keynotes, 9 invited papers and four doctoral papers were carefully reviewed and selected from 236 submissions. The papers are organized in topical sections on overview and research; policies and strategies; theoretical framework; related concepts; citizenship and digital divide; disadvantaged groups; information literacy for the workplace and daily life; information literacy in Europe; different approaches to information literacy; teaching and learning information literacy; information literacy instruction; assessment of information literacy; information literacy and K-12; information literacy and higher education; information literacy skills of LIS students; librarians, libraries and ethics.
