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Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities. This new fifth edition is an update and expansion of the rapid clinical and scientific advances in improving prognosis, and the impact of COVID-19, all of which has transformed conventional models of care. It covers basic science, such as how detailed understanding of the biology of the CFTR gene and protein has led to novel and beneficial therapies, as well as all aspects of clinical management in high-, middle- and low-income settings and the voices of individuals with CF from acros...
Film production in Latin America is as old as cinema itself, but local film industries have always been in a triangulated relationship with Hollywood and European cinema. This book situates Latin American film industries within the global circulation of film production, exhibition and distribution, charting the changes that the industries have undergone from the sound era to the present day. Focusing in particular on Argentina, Brazil and Mexico, Tamara Falicov examines commonalities among Latin American film industries, such as the challenges of procuring funding, competition from Hollywood, state funding battles, and the fickle nature of audiences, as well as censorship issues, competition...
This book provides a comprehensive overview of the multisystem disease, cystic fibrosis, for both pediatric and adult patients. Written by experts in the field, the text outlines the progressive nature of CF as well as the impact of this autosomal recessive disease on the respiratory, gastrointestinal, endocrine, rheumatologic, and renal systems, as well as the patient’s mental health. The book begins with a chapter describing the history of cystic fibrosis and how the face of this life-shortening disease has changed over the past several decades. The following chapters elucidate the pathophysiology of how cystic fibrosis impacts each organ system. Current management and therapeutics are detailed with step-by-step guidelines for clinicians. This book is unique in that it highlights the entire person, not just the respiratory system, with detailed inclusion of the patient perspectives throughout, informing practice standards and considerations. This is an ideal guide for pediatric and adult physicians who care for patients with cystic fibrosis, as well as respiratory therapists, physical therapists, nurses, nutritionists, and pharmacists who care for these patients.
If you are wondering what mobile technology adoption means for your library or how to get started, Mobile Technologies for Every Library will answer your questions! Wondering what the opportunities and pitfalls are of mobile technology use in libraries? This book will answer these questions. Thinking of starting a mobile program in your library? Want to improve on existing services or add new ones? This book will answer your questions about platforms, options, security, best practices and more. The book will preview many useful apps for libraries. Web links and resources are also included. Chapter coverage includes history and existing types of mobile technologies, mobile devices and supporting technology, ways to provide mobile technology for your users, a survey of currently available apps, ways to use mobile technology for library work, best practices, and future directions. Each chapter is organized by subtopics with tips and examples from real library programs to help you get started.
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Jan. 2003- : "7 directories in 1: section 1: alphabetical section; section 2: business section; section 3: telephone number section; section 4: street guide; section 5: map section; section 6: movers & shakers; section 7: demographic summary."
ROBETH (written in ANSI FORTRAN 77) is a systematized collection of algorithms that allows computation of a broad class of procedures based on M- and high-breakdown point estimation, including robust regression, robust testing of linear hypotheses, and robust coveriances. This book describes the computational procedures included in ROBETH. Each chapter is organized into three parts: 1. An overview of the theoretical background for the statistical and numerical methods 2. A detailed description of the corresponding FORTRAN subroutines and of the numerical algorithms as they are implemented 3. The scripts of several examples concerning the use of ROBETH by means of the S-PLUS interface, including some examples of high-level S functions.