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This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the likelihood of focal hyperinsulinism, is starting to emerge. The opening chapter discusses HI diagnosis using biochemical approaches and phenotype characterization. The various forms of HI are then pr...
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Und...
This issue of PET Clinics focuses on PET Imaging in Pediatric Patients and is edited by Drs. Hongming Zhuang and Abass Alavi. Articles will include: Promising New PET tracers in the evaluation of pediatric disease; F-DOPA PET/CT in the management of congenital hyperinsulinism; Emerging roles of PET/MRI in pediatric hospital; Roles of FDG PET/CT in the management of posttransplant lymphoproliferative disease in pediatric patient; FDG-PET/CT in the management of pediatric lymphoma; Preparation and logistic consideration in performing PET/CT and PET/MRI in pediatric patients; PET/CT in the evaluation of FUO and infectious/inflammatory disease in pediatric patients; Roles of PET/CT in the evaluation of neuroblastoma; Potential Roles of Total Body Imaging in Pediatric Diseases and Disorders; PET/CT in the Management of Pediatric Sarcomas; Pediatric Cardiac PET Imaging; Dosimetry between PET/CT and PET/MRI: Implications in Pediatric Imaging; Essential Role of Global Disease Assessment in Assessing Systemic Disorders, and more!
Advances in Pediatrics reviews the year's most important findings and updates within the field in order to provide pediatricians and primary care providers with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Carol Berkowitz, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in pediatrics inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. - Contains over 15 articles on such topics as Management of Congenital Adrenal Hyperpla...
Completely updated, the new edition of this easy-to-reference text examines the physiological, biochemical, and genetic aspects of pediatric endocrine disorders. Leaders in the field discuss the hottest topics-including genetics, diabetes and obesity-impacting today’s endocrine practice, keeping you up to date. A user-friendly organization speeds you to the information you need, and conceptual illustrations and photographs depict the latest advances with consistency and clarity. It’s the guidance you need to provide effective, state-of-the-art care for your pediatric and neonatal patients. Examines the physiological, biochemical, and genetic aspects of endocrine disorders all in one conv...
An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today's clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you're preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course fo...
Molecular mechanisms, clinical manifestations and new treatments In this volume of 'Frontiers in Diabetes' dealing with the molecular basis of monogenic disease of beta-cell insulin regulation, world-renowned experts provide in-depth descriptions of the many recent advances in genetic defects that cause hyperinsulinemic hypoglycemia. These disorders comprise the most important form of hypoglycemia in infants and children and are associated with a high risk of morbidity, including seizures and severe brain injury. The discovery of eight different genetic loci involved in congenital hyperinsulinism has led to greatly improved methods of diagnosis and treatment. New approaches to diagnosis are ...
Given the success of Research Topic Endocrine and Metabolic Effects on Maternal-fetal and Neonatal Outcomes and the rapidly evolving subject area, we are pleased to announce the launch of Volume II. Pregnancy is a complex state with many endocrine and metabolic challenges to a woman's physiology. Inappropriate maternal endocrine and metabolic changes such as obesity, hyperglycemia, hyperlipidemia, and hypothyroidism, may lead to short-term and long-term complications in the mother and offspring. This not only affects population health, but also imposes a huge social and economic burden, accompanied by significant direct and indirect public health costs. Therefore, the study of endocrine and ...
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
Find answers fast with The 5-Minute Pediatric Consult, 9th Edition—your go-to resource for the effective medical care of infants, children, and adolescents. Using the proven 5-Minute format, it provides rapid access to information on diagnosis, treatment, medications, follow-up, and associated factors for more than 530 diseases and conditions. The 5-Minute Pediatric Consult is designed to help you make quick, accurate decisions every day ... helping you save time and offer every patient the best possible care.