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Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory role of nc-RNAs exert in many biological processes. Overall, these studies are making increasingly clear that, both in model organisms and in humans, complexity is not a function of the number of protein-coding genes, but results from the possibility of using combinations of genetic programs and controlling their spatial and temporal regulation during development, s...
For more than ten years, the distinguished geneticists James F. Crow and William F. Dove have edited the popular "Perspectives" column in Genetics, the journal of the Genetics Society of America. This book, Perspectives on Genetics, collects more than 100 of these essays, which cumulatively are a history of modern genetics research and its continuing evolution.
A comparison of the use of model systems and exemplary cases across fields in the natural and social sciences.
This book, based on revised papers originally delivered at the VII International Systemic Functional Workshop in Valencia in 1995, explores some of the choices open to speakers and writers for the expression of meaning in different socio-cultural contexts. Many of the papers draw their inspiration from models of language developed by Michael Halliday and in particular recent theories of variation in relation to texts and genres explored by Halliday and his followers. There is an emphasis on the interdependence and interaction of linguistic choices across sentence boundaries and speaking turns, and also a consistent focus across many papers on the importance of lexicogrammar in the constructi...
Contributors to this symposium focus on the interface between genes and cells, covering genetic analysis, cloning studies, and the investigation of cell lineages and cellular interactions. They note how the body axes are already determined in the eggs of invertebrates and amphibia, then consider the mechanisms as the egg cleaves, in annelids, arthropods, amphibia, and mice that underlie assignation of cells to specific lineages, which give rise to different tissues in the adult. Closing chapters characterize the molecules that mediate each cell's particular fate, its position in the final body plan as the result of cell sorting or, in some cases, cell migration.
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-