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Biomimetic Organic Synthesis
In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature. Volume 1 describes the biomimetic synthesis of alkaloids. Volume 2 covers terpenes, polyketides, and polyphenols. A discussion of the current challenges and frontiers in biomimetic synthesis concludes this comprehensive handbook. Key features: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming, making this comprehensive 2 volume work a must-have for everyone working in the field. Unifying both synthetic and biosynthetic aspects, this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry.
Strategies and Tactics in Organic Synthesis
This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. There are stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners.
Catharanthus roseus
This volume provides updated technical approaches that have been developed to characterize monoterpene indole alkaloid metabolism in C. roseus from metabolite/gene product localization, alkaloid chemical synthesis, candidate gene prediction, transcription factor characterization up to functional genomic tools based on gene overexpression. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Catharanthus roseus: Methods and Protocols aims to be a guidebook to all researchers working at characterizing alkaloid biosynthesis and more broadly specialized metabolisms
Organic Synthesis
Organic synthesis is a vibrant and rapidly evolving field; we can now cyclize amines directly onto alkenes. Like the first two books in this series, Organic Synthesis: State of the Art 2003-2005 and Organic Synthesis: State of the Art 2005-2007, this reference leads readers quickly to the most important recent developments. Two years of Taber's popular weekly online column, "Organic Chemistry Highlights", as featured on the organic-chemistry.org website, are consolidated here, with cumulative indices of all three volumes in this series. Important topics that are covered range from powerful new methods for C-C bond construction to asymmetric organocatalysis and direct C-H functionalization. This go-to reference focuses on the most important recent developments in organic synthesis, and includes a succinct analysis of the significance and applicability of each new synthetic method. It details and analyzes more than twenty complex total syntheses, including the Sammakia synthesis of the Macrolide RK-397, the Ley synthesis of Rapamycin, and the Kobayashi synthesis of (-)-Norzoanthamine.
I, Rapid Access to [4.3.1]propellanes Via Fischer Carbene Complexes
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Total Synthesis of Norrisolide, Synthesis of Norrisolide Analogues, and Biological Evaluation of Norrisolide Probes
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Pharmacognosie
L'OUVRAGELa pharmacognosie est l'étude des substances médicamenteuses d'origine naturelle : végétale, animale ou microbienne. Traité de façon claire et synthétique, le cours s'articule en 23 chapitres regroupés ainsi : - Généralités sur les substances naturelles et grandes classes de produits naturels ;- Modes d'obtention, de production et de contrôle des substances médicamenteuses d'origine naturelle ;- Substances actives classées selon leurs indications thérapeutiques ;- Substances naturelles à prescription médicale facultative.La première partie présente les bases de la pharmacognosie et concerne plus particulièrement les étudiants de 2e année. La deuxième partie li...
Organic Synthesis
A concise reference that summarizes the most important current developments in organic synthesis.
Nouvelles drôles d'histoires de médicaments d'origine naturelle
Les principaux protagonistes de ces Nouvelles drôles d'histoires de médicaments d'origine naturelle sont avant tout des molécules et leurs sources naturelles respectives, végétale, animale ou microbienne. Presque tous les principes actifs présentés dans ce livre sont indiqués dans des pathologies graves (les maladies infectieuses, la goutte, la sclérose en plaques, la douleur, la toxicomanie, les thromboses, les rejets de greffe, les cancers...). Si les médicaments se taillent la part du lion dans ce livre, les humains n'ont pas été exclus du générique : le lecteur y trouvera des noms bien connus (par exemple Fleming, Florey et Chain, Howell et McLean, Pelletier et Caventou, ou...
