Seems you have not registered as a member of localhost.saystem.shop!
You may have to register before you can download all our books and magazines, click the sign up button below to create a free account.
Arterial Chemoreceptors in Physiology and Pathophysiology
Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds, UK during the summer of 2014. As such this volume represents a unique collection of state of the art reviews and original, brief research articles covering all aspects of oxygen sensing, ranging from the molecular mechanisms of chemotransduction in oxygen sensing cells such as the carotid body type I cells, to the adverse, reflex cardiovascular outcomes arising from carotid body dysfunction as seen, for example, in heart failure or obstructive sleep apnoea. This volume will be of tremendous interest to basic scientists with an interest in the cellular and molecular biology of oxygen sensing and integrative, whole organism physiologists as well as physicians studying or treating the clinical cardiovascular consequences of carotid body dysfunction.
Arterial Chemoreceptors
This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date information concerning the carotid body and oxygen sensing in health and disease. This volume is a required text for all researchers in the field of arterial chemoreception and will provide a valuable reference source for years to come.
Arterial Chemoreceptors
The book will contain reviews and brief research articles from the participants attending the International Society for Arterial Chemoreception (ISAC) meeting, to be held in Lisbon in Portugal in June/July 2020. Since ISAC was first established, almost 70 years ago, many advances in the classical field of arterial O2, CO2 and pH sensing have been achieved but the most impressive ones are probably related to the non-canonical roles of the carotid body, as its involvement in sympatho-mediated diseases. Over the recent years, the carotid body field has gained attention with the findings that carotid body dysfunction is associated with the development/maintenance of highly prevalent diseases fro...
Avery's Diseases of the Newborn: First South Asia Edition-E-Book
Covering the evaluation and management of every key disease and condition affecting newborns, Avery's Diseases of the Newborn, by Drs. Christine A. Gleason and Sandra E. Juul, remains your #1 source for practical, clinically relevant information in this fast-changing field. You'll find the specific strategies you need to confidently diagnose and treat this unique patient population, easy-to-use single volume that focuses on key areas of practice. Now in a thoroughly revised first South Asia Edition, this highly respected reference is an authoritative clinical resource for neonatal practitioners. Provides up-to-date information on every aspect of newborn evaluation and management in a new, vi...
Toxicity Testing in the 21st Century
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Guidelines for the Humane Transportation of Research Animals
Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transporta...
Arterial Chemoreception
Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis. Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.
The Arterial Chemoreceptors
This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.
Frontiers in Arterial Chemoreception
Proceedings of the XIIIth International Symposium, held in Santiago, Chile, March 25-29, 1996
Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents
The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterroris...
